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Zinc Chloride Side Effects

The most commonly reported side effects of zinc chloride include macular degeneration, nausea, and malaise, based on 187 FDA adverse event reports from 2004 to 2025. 46.0% of reports found the drug to be ineffective.

Zinc Chloride side effects

Percentages show how often each reaction appears relative to total reports for zinc chloride.

1
Drug Ineffective46.0%86
2
Macular Degeneration44.9%84
3
Nausea30.5%57
4
Malaise28.9%54
5
Pain28.3%53
6
Pyrexia28.3%53
7
Weight Decreased28.3%53
8
Off Label Use27.8%52
9
Dyspepsia27.8%52
10
Paraesthesia Oral27.8%52
11
Therapeutic Product Effect Incomplete27.8%52
12
Chronic Sinusitis27.3%51
13
Infusion Related Reaction26.7%50
14
Procedural Pain26.7%50
15
Headache24.1%45

These are voluntary reports and do not establish that zinc chloride caused these reactions.

Report severity

67.9%Serious127 reports
40.6%Hospitalizations76 reports
5.3%Fatal10 reports

Seriousness is determined by the reporter, not by OpenClaim.

Zinc Chloride drug interactions

Other drugs that appear in adverse event reports alongside zinc chloride. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Triamcinolone44.9%84
2
Magnesium-sulfate44.4%83
3
Ergocalciferol43.9%82
4
Sodium-chloride43.3%81
5
Morphine-sulfate43.3%81
6
Pantoprazole-sodium43.3%81
7
Amoxicillin42.8%80
8
Cetirizine-hydrochloride42.8%80
9
Betamethasone42.8%80
10
Acetaminophen42.8%80
11
Mupirocin42.8%80
12
Atorvastatin-calcium42.8%80
13
Adalimumab42.8%80
14
Diphenhydramine42.8%80
15
Alprazolam42.2%79

Taken alongside

1
Calcium24.6%46
2
Valsartan24.6%46
3
Ergocalciferol20.9%39
4
Diphenhydramine19.8%37
5
Ascorbic-acid13.9%26
6
Metoclopramide-hydrochloride12.3%23
7
Amoxicillin11.2%21
8
Pantoprazole-sodium10.7%20
9
Aspirin10.7%20
10
Acetaminophen10.2%19
11
Folic-acid9.6%18
12
Hydrochlorothiazide9.6%18
13
Atorvastatin-calcium9.1%17
14
Loperamide-hydrochloride8.0%15
15
Fluticasone8.0%15

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports zinc chloride side effects

74.9% of zinc chloride adverse event reports involve female patients and 17.1% involve male patients. The largest age group is elderly at 65%. These figures reflect who reports side effects, not underlying risk.

Sex

Female74.9%
Male17.1%
Unknown8.0%

Age group

< 26.5%
2–110.8%
12–171.6%
18–6426.0%
65+65.0%

What is zinc chloride used for

Conditions and purposes for which patients were taking zinc chloride when the adverse event was reported.

AlopeciaAstringent TherapyAcneChest PainCoronary Artery DiseaseFatigueFoetal Exposure During PregnancyGated Single Photon Emission Computerised TomogramHerpes ZosterIntestinal PerforationIschaemic CardiomyopathyImmune System DisorderMineral SupplementationNasopharyngitisPain

Showing 15 of 22 indications

Zinc Chloride brand names and reporting trend

Zinc Chloride is sold under the brand name Zinc Chloride In Plastic Container.

Brand names

Zinc Chloride In Plastic Container196

Quarterly reports (20042025)

200420202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking zinc chloride with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.