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Ziftomenib Side Effects

The most commonly reported side effects of ziftomenib include death, and red blood cell count decreased, based on 3 FDA adverse event reports from 2025 to 2025. 33.3% of reports found the drug to be ineffective.

Ziftomenib side effects

Percentages show how often each reaction appears relative to total reports for ziftomenib.

1
Drug Ineffective33.3%1
2
Death33.3%1
3
Red Blood Cell Count Decreased33.3%1

These are voluntary reports and do not establish that ziftomenib caused these reactions.

Report severity

100.0%Serious3 reports
0.0%Hospitalizations0 reports
33.3%Fatal1 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ziftomenib drug interactions

Other drugs that appear in adverse event reports alongside ziftomenib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Venetoclax100.0%3
2
Gilteritinib-fumarate33.3%1
3
Decitabine33.3%1

Taken alongside

1
Ondansetron66.7%2
2
Ergocalciferol66.7%2
3
Losartan-potassium66.7%2
4
Allopurinol66.7%2
5
Voriconazole66.7%2
6
Acyclovir66.7%2
7
Levofloxacin33.3%1
8
Cetirizine-hydrochloride33.3%1
9
Prochlorperazine33.3%1
10
Metformin33.3%1
11
Levothyroxine-sodium33.3%1
12
Micafungin-sodium33.3%1
13
Citalopram-hydrobromide33.3%1
14
Famotidine33.3%1
15
Tramadol-hydrochloride33.3%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ziftomenib side effects

66.7% of ziftomenib adverse event reports involve female patients and 33.3% involve male patients. The largest age group is adult at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female66.7%
Male33.3%
Unknown0.0%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6466.7%
65+33.3%

What is ziftomenib used for

Conditions and purposes for which patients were taking ziftomenib when the adverse event was reported.

Acute Myeloid Leukaemia (in Remission)Product Used For Unknown Indication

Ziftomenib brand names and reporting trend

Ziftomenib is sold under the brand name Komzifti.

Brand names

Komzifti3

Quarterly reports (20252025)

20252025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ziftomenib with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.