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Vinorelbine Side Effects

The most commonly reported side effects of vinorelbine include disease progression, off label use, and malignant neoplasm progression, based on 12,839 FDA adverse event reports from 2004 to 2025. 4.7% of reports found the drug to be ineffective.

Vinorelbine side effects

Percentages show how often each reaction appears relative to total reports for vinorelbine.

1
Disease Progression8.5%1,097
2
Off Label Use8.2%1,047
3
Malignant Neoplasm Progression8.0%1,027
4
Neutropenia6.8%871
5
Nausea6.6%841
6
Fatigue5.8%749
7
Diarrhoea5.6%722
8
Death4.8%618
9
Drug Ineffective4.7%609
10
Vomiting4.7%601
11
Anaemia4.6%592
12
Dyspnoea4.2%535
13
Pyrexia4.1%529
14
Febrile Neutropenia3.8%484
15
Thrombocytopenia3.7%480

These are voluntary reports and do not establish that vinorelbine caused these reactions.

Report severity

96.2%Serious12,354 reports
35.3%Hospitalizations4,533 reports
21.4%Fatal2,749 reports

Seriousness is determined by the reporter, not by OpenClaim.

Vinorelbine drug interactions

Other drugs that appear in adverse event reports alongside vinorelbine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Trastuzumab22.5%2,885
2
Capecitabine20.6%2,641
3
Gemcitabine20.4%2,619
4
Cisplatin15.7%2,020
5
Carboplatin15.7%2,010
6
Paclitaxel14.2%1,823
7
Docetaxel13.4%1,719
8
Doxorubicin-hydrochloride12.5%1,610
9
Cyclophosphamide11.8%1,518
10
Bevacizumab7.7%983
11
Lapatinib-ditosylate7.1%914
12
Pertuzumab6.3%803
13
Zoledronic-acid5.3%683
14
Vincristine-sulfate5.2%674
15
Fulvestrant5.2%670

Taken alongside

1
Dexamethasone8.7%1,114
2
Paclitaxel7.0%893
3
Gemcitabine6.7%855
4
Docetaxel5.6%719
5
Ondansetron5.1%660
6
Carboplatin5.0%644
7
Acetaminophen4.9%630
8
Cyclophosphamide4.2%535
9
Cisplatin4.1%532
10
Doxorubicin-hydrochloride4.0%516
11
Capecitabine3.7%481
12
Pantoprazole-sodium3.2%415
13
Zoledronic-acid2.9%367
14
Trastuzumab2.7%352
15
Prednisone2.7%346

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports vinorelbine side effects

60.2% of vinorelbine adverse event reports involve female patients and 25.9% involve male patients. The largest age group is adult at 62%. These figures reflect who reports side effects, not underlying risk.

Sex

Female60.2%
Male25.9%
Unknown14.0%

Age group

< 20.5%
2–112.0%
12–173.2%
18–6461.6%
65+32.7%

What is vinorelbine used for

Conditions and purposes for which patients were taking vinorelbine when the adverse event was reported.

Accidental ExposureAcute Biphenotypic LeukaemiaAcute LeukaemiaAcute Lymphocytic LeukaemiaAcute Lymphocytic Leukaemia RecurrentAcute Myeloid LeukaemiaAcute Myeloid Leukaemia RecurrentAcute Myeloid Leukaemia RefractoryAcute Myelomonocytic LeukaemiaAdenocarcinomaAdenocarcinoma MetastaticAdenocarcinoma Of Salivary GlandAdenoid Cystic CarcinomaAdenoma BenignAdenosquamous Cell Carcinoma

Showing 15 of 625 indications

Vinorelbine brand names and reporting trend

Vinorelbine is sold under the brand name Vinorelbine Tartrate.

Brand names

Vinorelbine Tartrate47

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking vinorelbine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.