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Viloxazine Side Effects

The most commonly reported side effects of viloxazine include headache, vomiting, and nausea, based on 1,004 FDA adverse event reports from 2005 to 2025. 5.8% of reports found the drug to be ineffective.

Viloxazine side effects

Percentages show how often each reaction appears relative to total reports for viloxazine.

1
Headache12.0%120
2
Vomiting10.9%109
3
Nausea10.5%105
4
Fatigue9.4%94
5
Migraine9.0%90
6
Insomnia8.3%83
7
Somnolence7.6%76
8
Suicidal Ideation7.0%70
9
Drug Ineffective5.8%58
10
Anxiety5.3%53
11
Withdrawal Syndrome4.9%49
12
Irritability3.9%39
13
Product Dose Omission Issue3.7%37
14
Anger3.5%35
15
Decreased Appetite2.9%29

These are voluntary reports and do not establish that viloxazine caused these reactions.

Report severity

35.9%Serious360 reports
9.5%Hospitalizations95 reports
1.0%Fatal10 reports

Seriousness is determined by the reporter, not by OpenClaim.

Viloxazine drug interactions

Other drugs that appear in adverse event reports alongside viloxazine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Bupropion1.6%16
2
Methylphenidate1.6%16
3
Dupilumab1.6%16
4
Sodium-oxybate1.4%14
5
Dextromethorphan1.2%12
6
Sertraline-hydrochloride1.2%12
7
Venlafaxine1.1%11
8
Buprenorphine1.1%11
9
Atomoxetine-hydrochloride1.0%10
10
Aripiprazole1.0%10
11
Hydroxyzine0.9%9
12
Quetiapine-fumarate0.9%9
13
Lurasidone-hydrochloride0.8%8
14
Clonidine0.8%8
15
Esketamine-hydrochloride0.8%8

Taken alongside

1
Ergocalciferol6.0%60
2
Bupropion4.9%49
3
Sertraline-hydrochloride4.6%46
4
Escitalopram-oxalate4.3%43
5
Cetirizine-hydrochloride3.7%37
6
Hydroxyzine3.6%36
7
Fluoxetine-hydrochloride3.5%35
8
Gabapentin3.2%32
9
Amphetamine3.1%31
10
Dextroamphetamine3.1%31
11
Guanfacine-hydrochloride3.0%30
12
Methylphenidate2.9%29
13
Acetaminophen2.8%28
14
Ibuprofen2.6%26
15
Albuterol2.6%26

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports viloxazine side effects

41.7% of viloxazine adverse event reports involve female patients and 43.2% involve male patients. The largest age group is adult at 47%. These figures reflect who reports side effects, not underlying risk.

Sex

Female41.7%
Male43.2%
Unknown15.0%

Age group

< 20.0%
2–1128.8%
12–1721.6%
18–6447.3%
65+2.3%

What is viloxazine used for

Conditions and purposes for which patients were taking viloxazine when the adverse event was reported.

Antibiotic TherapyAttention Deficit Hyperactivity DisorderAbnormal BehaviourAffective DisorderAngerAnxietyAttention Deficit Hyperactivity DisorderAutism Spectrum DisorderBlood Antidiuretic HormoneCryingDepressionDepressionDisruptive Mood Dysregulation DisorderDisturbance In AttentionEmotional Distress

Showing 15 of 27 indications

Viloxazine brand names and reporting trend

Viloxazine is sold under the brand name Qelbree.

Brand names

Qelbree69

Quarterly reports (20052025)

20052025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking viloxazine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.