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Verteporfin Side Effects

The most commonly reported side effects of verteporfin include visual acuity reduced, visual acuity reduced, and polypoidal choroidal vasculopathy, based on 1,641 FDA adverse event reports from 2004 to 2025.

Verteporfin side effects

Percentages show how often each reaction appears relative to total reports for verteporfin.

1
Visual Acuity Reduced14.3%234
2
Visual Acuity Reduced12.1%198
3
Polypoidal Choroidal Vasculopathy8.4%138
4
Retinal Haemorrhage8.2%135
5
Off Label Use8.2%135
6
Disease Progression7.6%125
7
Retinal Haemorrhage6.0%98
8
Age-related Macular Degeneration5.7%93
9
Choroidal Neovascularisation3.6%59
10
Disease Progression3.6%59
11
Product Use In Unapproved Indication3.5%57
12
Retinal Pigment Epithelial Tear3.4%55
13
Choroidal Neovascularisation3.2%53
14
Retinal Detachment2.8%46
15
Detachment Of Retinal Pigment Epithelium2.8%46

These are voluntary reports and do not establish that verteporfin caused these reactions.

Report severity

89.6%Serious1,470 reports
13.0%Hospitalizations214 reports
4.0%Fatal65 reports

Seriousness is determined by the reporter, not by OpenClaim.

Verteporfin drug interactions

Other drugs that appear in adverse event reports alongside verteporfin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ranibizumab33.6%552
2
Bevacizumab5.9%97
3
Aflibercept4.4%72
4
Triamcinolone4.3%71
5
Dexamethasone0.7%11
6
Pegaptanib-sodium0.6%10
7
Brolucizumab-dbll0.5%9
8
Warfarin0.4%7
9
Fluorescein-sodium0.3%5
10
Tobramycin0.3%5
11
Indocyanine-green0.2%4
12
Teriparatide0.1%2
13
Raloxifene-hydrochloride0.1%2
14
Clopidogrel-bisulfate0.1%2
15
Prednisone0.1%2

Taken alongside

1
Aflibercept6.9%114
2
Aspirin3.7%60
3
Triamcinolone2.8%46
4
Amlodipine2.7%44
5
Levofloxacin2.3%38
6
Atorvastatin-calcium2.1%34
7
Levothyroxine-sodium2.0%32
8
Moxifloxacin-hydrochloride2.0%32
9
Hydrochlorothiazide1.8%29
10
Fluorescein-sodium1.7%28
11
Warfarin1.6%27
12
Lisinopril1.5%24
13
Furosemide1.5%24
14
Metoprolol1.4%23
15
Bevacizumab1.3%21

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports verteporfin side effects

38.1% of verteporfin adverse event reports involve female patients and 52.4% involve male patients. The largest age group is elderly at 72%. These figures reflect who reports side effects, not underlying risk.

Sex

Female38.1%
Male52.4%
Unknown9.4%

Age group

< 20.2%
2–110.6%
12–170.9%
18–6426.3%
65+72.0%

What is verteporfin used for

Conditions and purposes for which patients were taking verteporfin when the adverse event was reported.

Age-related Macular DegenerationAnisometropiaAge-related Macular DegenerationAntibiotic ProphylaxisBenign NeoplasmBenign Neoplasm Of ChoroidBrain Neoplasm MalignantChorioretinal AtrophyChorioretinal DisorderChorioretinopathyChoroid MelanomaChoroid NeoplasmChoroidal DystrophyChoroidal HaemangiomaChoroidal Neovascularisation

Showing 15 of 103 indications

Verteporfin brand names and reporting trend

Verteporfin is sold under the brand name Visudyne.

Brand names

Visudyne216

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking verteporfin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.