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Verapamil Side Effects

The most commonly reported side effects of verapamil include dyspnoea, fatigue, and nausea, based on 48,206 FDA adverse event reports from 2004 to 2025. 4.6% of reports found the drug to be ineffective.

Verapamil side effects

Percentages show how often each reaction appears relative to total reports for verapamil.

1
Drug Ineffective4.6%2,227
2
Dyspnoea4.1%1,956
3
Fatigue3.9%1,894
4
Nausea3.7%1,772
5
Headache3.4%1,615
6
Dizziness3.3%1,576
7
Off Label Use3.2%1,562
8
Diarrhoea3.1%1,500
9
Completed Suicide3.0%1,458
10
Hypotension2.9%1,391
11
Drug Interaction2.7%1,324
12
Toxicity To Various Agents2.7%1,317
13
Malaise2.7%1,300
14
Fall2.7%1,284
15
Asthenia2.5%1,213

These are voluntary reports and do not establish that verapamil caused these reactions.

Report severity

74.5%Serious35,930 reports
38.6%Hospitalizations18,587 reports
14.8%Fatal7,115 reports

Seriousness is determined by the reporter, not by OpenClaim.

Verapamil drug interactions

Other drugs that appear in adverse event reports alongside verapamil. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab3.6%1,736
2
Omeprazole2.6%1,271
3
Acetaminophen2.4%1,167
4
Atorvastatin-calcium2.2%1,075
5
Aspirin2.2%1,064
6
Pregabalin2.0%976
7
Hydrochlorothiazide2.0%975
8
Metformin2.0%969
9
Metoprolol1.9%912
10
Lenalidomide1.9%896
11
Furosemide1.8%860
12
Esomeprazole1.8%849
13
Sodium-oxybate1.7%825
14
Simvastatin1.7%803
15
Etanercept1.6%775

Taken alongside

1
Aspirin13.6%6,575
2
Acetaminophen11.0%5,296
3
Furosemide10.8%5,212
4
Levothyroxine-sodium10.1%4,867
5
Atorvastatin-calcium9.0%4,351
6
Albuterol9.0%4,340
7
Hydrochlorothiazide8.8%4,234
8
Omeprazole8.7%4,214
9
Ergocalciferol8.0%3,842
10
Metformin7.6%3,674
11
Lisinopril7.2%3,489
12
Gabapentin6.6%3,162
13
Prednisone6.3%3,042
14
Fluticasone6.2%2,983
15
Metoprolol6.0%2,901

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports verapamil side effects

59.6% of verapamil adverse event reports involve female patients and 32.6% involve male patients. The largest age group is elderly at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female59.6%
Male32.6%
Unknown7.7%

Age group

< 20.4%
2–110.3%
12–171.0%
18–6447.0%
65+51.4%

What is verapamil used for

Conditions and purposes for which patients were taking verapamil when the adverse event was reported.

Abdominal DiscomfortAbdominal PainAccelerated HypertensionAccelerated Idioventricular RhythmAccidental ExposureAccidental OverdoseAcute Coronary SyndromeAcute Kidney InjuryAcute Myocardial InfarctionAcute Pulmonary OedemaAdenoma BenignAdrenal DisorderAdverse EventAffective DisorderAge Indeterminate Myocardial Infarction

Showing 15 of 666 indications

Verapamil brand names and reporting trend

Verapamil is sold under the brand name Verapamil Hcl.

Brand names

Verapamil Hcl29

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking verapamil with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.