OpenClaim

Velaglucerase Side Effects

The most commonly reported side effects of velaglucerase include inappropriate schedule of product administration, product dose omission issue, and covid-19, based on 1,980 FDA adverse event reports from 2010 to 2025.

Velaglucerase side effects

Percentages show how often each reaction appears relative to total reports for velaglucerase.

1
Inappropriate Schedule Of Product Administration10.3%204
2
Product Dose Omission Issue9.7%193
3
Covid-198.3%165
4
Fatigue7.4%147
5
Death6.0%118
6
Pyrexia5.5%108
7
Fall5.4%107
8
Malaise5.3%105
9
Headache5.0%99
10
Weight Increased4.9%97
11
Arthralgia4.7%94
12
Infusion Related Reaction4.6%91
13
Nausea4.4%87
14
Weight Decreased4.2%84
15
Abdominal Pain4.2%83

These are voluntary reports and do not establish that velaglucerase caused these reactions.

Report severity

83.6%Serious1,655 reports
42.8%Hospitalizations848 reports
13.6%Fatal269 reports

Seriousness is determined by the reporter, not by OpenClaim.

Velaglucerase drug interactions

Other drugs that appear in adverse event reports alongside velaglucerase. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Imiglucerase1.9%38
2
Eliglustat-tartrate0.5%9
3
Acetaminophen0.4%8
4
Miglustat0.4%7
5
Risedronate-sodium0.4%7
6
Tramadol-hydrochloride0.4%7
7
Levocetirizine-dihydrochloride0.3%5
8
Ramipril0.3%5
9
Metoprolol0.3%5
10
Taliglucerase-alfa0.2%4
11
Dapagliflozin0.2%4
12
Albuterol0.2%4
13
Levetiracetam0.2%4
14
Diphenhydramine0.2%3
15
Ticagrelor0.2%3

Taken alongside

1
Acetaminophen5.5%108
2
Ergocalciferol4.4%88
3
Diphenhydramine4.0%80
4
Sodium-chloride3.9%78
5
Sterile3.8%76
6
Epinephrine3.8%76
7
Aspirin3.0%59
8
Omeprazole2.7%53
9
Atorvastatin-calcium2.2%44
10
Amlodipine2.2%43
11
Ibuprofen2.1%41
12
Gabapentin2.1%41
13
Levetiracetam2.0%40
14
Metformin1.9%37
15
Imiglucerase1.8%35

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports velaglucerase side effects

49.3% of velaglucerase adverse event reports involve female patients and 39.8% involve male patients. The largest age group is adult at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female49.3%
Male39.8%
Unknown10.9%

Age group

< 23.5%
2–1110.2%
12–175.9%
18–6453.5%
65+26.9%

What is velaglucerase used for

Conditions and purposes for which patients were taking velaglucerase when the adverse event was reported.

AsthmaAsthmatic CrisisBone PainBlood Immunoglobulin M DecreasedExposure During Breast FeedingEnzyme AbnormalityEnzyme SupplementationFabry^s DiseaseFoetal Exposure During PregnancyFabry^s DiseaseGaucher's DiseaseGaucher^s DiseaseGaucher^s Disease Type IGaucher^s Disease Type IiGaucher^s Disease Type Iii

Showing 15 of 53 indications

Velaglucerase brand names and reporting trend

Velaglucerase is sold under the brand name Vpriv.

Brand names

Vpriv3,806

Quarterly reports (20102025)

201020122016202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking velaglucerase with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.