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Vasopressin Side Effects

The most commonly reported side effects of vasopressin include off label use, hypotension, and multiple organ dysfunction syndrome, based on 4,653 FDA adverse event reports from 2004 to 2025. 27.7% of reports found the drug to be ineffective.

Vasopressin side effects

Percentages show how often each reaction appears relative to total reports for vasopressin.

1
Drug Ineffective27.7%1,289
2
Off Label Use11.6%538
3
Hypotension10.4%483
4
Multiple Organ Dysfunction Syndrome8.6%398
5
Cardiogenic Shock8.1%379
6
Sepsis7.9%368
7
Condition Aggravated7.7%360
8
Acute Kidney Injury7.0%327
9
Toxicity To Various Agents6.9%321
10
Vomiting6.2%290
11
Hyponatraemia5.8%271
12
Abdominal Pain5.7%264
13
General Physical Health Deterioration5.5%258
14
Ascites5.5%257
15
Nausea5.5%256

These are voluntary reports and do not establish that vasopressin caused these reactions.

Report severity

96.4%Serious4,485 reports
55.2%Hospitalizations2,570 reports
40.2%Fatal1,869 reports

Seriousness is determined by the reporter, not by OpenClaim.

Vasopressin drug interactions

Other drugs that appear in adverse event reports alongside vasopressin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Epinephrine38.3%1,780
2
Dobutamine-hydrochloride11.3%525
3
Phenylephrine10.3%481
4
Heparin10.0%463
5
Amiodarone-hydrochloride8.2%380
6
Ceftriaxone-sodium8.0%370
7
Norepinephrine-bitartrate7.9%366
8
Hydrocortisone7.4%343
9
Lansoprazole7.1%330
10
Insulin6.9%322
11
Gabapentin6.9%321
12
Dextrose6.8%317
13
Acetaminophen6.8%315
14
Metronidazole6.7%313
15
Albuterol6.6%309

Taken alongside

1
Epinephrine36.8%1,712
2
Fentanyl16.2%755
3
Vancomycin15.0%696
4
Midazolam14.5%675
5
Heparin13.2%612
6
Furosemide12.2%569
7
Insulin11.8%549
8
Propofol11.8%548
9
Acetaminophen10.1%469
10
Hydrocortisone9.9%459
11
Potassium-chloride9.5%441
12
Phenylephrine9.3%432
13
Sodium-bicarbonate8.9%416
14
Pantoprazole-sodium8.6%400
15
Dobutamine-hydrochloride8.1%378

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports vasopressin side effects

38.7% of vasopressin adverse event reports involve female patients and 52.4% involve male patients. The largest age group is adult at 58%. These figures reflect who reports side effects, not underlying risk.

Sex

Female38.7%
Male52.4%
Unknown8.9%

Age group

< 25.3%
2–112.3%
12–174.4%
18–6457.9%
65+30.1%

What is vasopressin used for

Conditions and purposes for which patients were taking vasopressin when the adverse event was reported.

Abortion InducedAcute Kidney InjuryAcute Myeloid LeukaemiaAcute Respiratory Distress SyndromeAdrenal InsufficiencyAdverse EventAnaesthesiaArrhythmiaAcidosisAcute Kidney InjuryAcute Respiratory Distress SyndromeAcute Respiratory FailureAdrenal InsufficiencyAlcohol PoisoningAnaesthesia

Showing 15 of 329 indications

Vasopressin brand names and reporting trend

Vasopressin is sold under brand names including Vasopressin In Sodium Chloride 0.9%, Pitressin Tannate.

Brand names

Vasopressin In Sodium Chloride 0.9%6,126
Pitressin Tannate8

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking vasopressin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.