Percentages show how often each reaction appears relative to total reports for valproic.
1 Drug Ineffective 9.5% 3,780
2 Drug Interaction 8.0% 3,176
5 Toxicity To Various Agents 4.9% 1,943
9 Condition Aggravated 2.5% 982
10 Foetal Exposure During Pregnancy 2.4% 941
13 Product Use In Unapproved Indication 2.2% 886
These are voluntary reports and do not establish that valproic caused these reactions.
Report severity
94.3% Serious 37,459 reports
44.0% Hospitalizations 17,496 reports
14.4% Fatal 5,714 reports
Seriousness is determined by the reporter, not by OpenClaim.
Valproic drug interactions
Other drugs that appear in adverse event reports alongside valproic. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
3 Quetiapine-fumarate 8.6% 3,417
15 Sertraline-hydrochloride 3.1% 1,244
Taken alongside
6 Quetiapine-fumarate 3.0% 1,210
10 Levothyroxine-sodium 2.8% 1,123
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
Who reports valproic side effects
41.6% of valproic adverse event reports involve female patients and 47.0% involve male patients. The largest age group is adult at 63%. These figures reflect who reports side effects, not underlying risk.
Sex
Female 41.6%
Male 47.0%
Unknown 11.4%
Age group
< 2 4.0%
2–11 12.0%
12–17 6.0%
18–64 63.1%
65+ 14.8%
What is valproic used for
Conditions and purposes for which patients were taking valproic when the adverse event was reported.
Abdominal Pain Upper Abnormal Behaviour Abstains From Alcohol Accidental Drug Intake By Child Accidental Exposure Accidental Exposure To Product By Child Accidental Overdose Acquired Epileptic Aphasia Acute Lymphocytic Leukaemia Recurrent Acute Myeloid Leukaemia Acute Psychosis Adjustment Disorder Adjustment Disorder With Depressed Mood Affect Lability Affective Disorder
Showing 15 of 1,002 indications
ABDOMINAL PAIN UPPER ABNORMAL BEHAVIOUR ABSTAINS FROM ALCOHOL ACCIDENTAL DRUG INTAKE BY CHILD ACCIDENTAL EXPOSURE ACCIDENTAL EXPOSURE TO PRODUCT BY CHILD ACCIDENTAL OVERDOSE ACQUIRED EPILEPTIC APHASIA ACUTE LYMPHOCYTIC LEUKAEMIA RECURRENT ACUTE MYELOID LEUKAEMIA ACUTE PSYCHOSIS ADJUSTMENT DISORDER ADJUSTMENT DISORDER WITH DEPRESSED MOOD AFFECT LABILITY AFFECTIVE DISORDER AGGRESSION AGITATION AGORAPHOBIA AKATHISIA ALCOHOL ABUSE ALCOHOLISM ALPERS' DISEASE AMAUROTIC FAMILIAL IDIOCY ANALGESIA ANALGESIC THERAPY ANAPLASTIC THYROID CANCER ANEURYSM ANGELMAN^S SYNDROME ANGER ANOXIA ANOXIC ENCEPHALOPATHY ANTIBIOTIC THERAPY ANTICONVULSANT DRUG LEVEL ANTIDEPRESSANT THERAPY ANTIPSYCHOTIC DRUG LEVEL ANTIPYRESIS ANTISOCIAL BEHAVIOUR ANTISOCIAL PERSONALITY DISORDER ANXIETY ANXIETY DISORDER APHASIA APPETITE DISORDER ARRHYTHMIA ASPERGER^S DISORDER ASTHMA ASTROCYTOMA, LOW GRADE ATONIC SEIZURES ATRIAL FIBRILLATION ATTENTION DEFICIT HYPERACTIVITY DISORDER ATTENTION DEFICIT/HYPERACTIVITY DISORDER ATYPICAL BENIGN PARTIAL EPILEPSY AURA AUTISM AUTISM SPECTRUM DISORDER AUTOIMMUNE ENCEPHALOPATHY AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME AUTOMATISM AUTOMATISM EPILEPTIC AUTONOMIC NERVOUS SYSTEM IMBALANCE AUTOSOMAL CHROMOSOME ANOMALY Abnormal behaviour Abortion threatened Abulia Acquired epileptic aphasia Acute myeloid leukaemia Acute post asthmatic amyotrophy Acute psychosis Adjustment disorder with depressed mood Adjuvant therapy Adverse drug reaction Affect lability Affective disorder Aggression Agitated depression Agitation Aicardi-Goutieres syndrome Alcohol abuse Alcohol use disorder Alcohol withdrawal syndrome Alternating hemiplegia of childhood Analgesic therapy Angelman^s syndrome Anger Anhedonia Ankylosing spondylitis Antibiotic therapy Antidepressant therapy Antiplatelet therapy Antipsychotic therapy Antisocial personality disorder Anxiety Anxiety disorder Astrocytoma malignant Ataxia Atonic seizures Atrial fibrillation Attention deficit hyperactivity disorder Autism spectrum disorder Autoimmune thyroiditis Automatism epileptic Autonomic nervous system imbalance Autonomic seizure BALANCE DISORDER BALLISMUS BALTIC MYOCLONIC EPILEPSY BEHAVIOUR DISORDER BEHAVIOURAL AND PSYCHIATRIC SYMPTOMS OF DEMENTIA BEHAVIOURAL THERAPY BENIGN ROLANDIC EPILEPSY BIPOLAR DISORDER BIPOLAR DISORDER RELAPSE PROPHYLAXIS BIPOLAR I DISORDER BIPOLAR II DISORDER BLEPHAROSPASM BLUNTED AFFECT BORDERLINE PERSONALITY DISORDER BRADYKINESIA BRAIN ABSCESS BRAIN CONTUSION BRAIN INJURY BRAIN MASS BRAIN NEOPLASM BRAIN NEOPLASM MALIGNANT BRAIN OPERATION BRAIN STEM GLIOMA BRAIN TUMOUR OPERATION BREAST CANCER METASTATIC BRIEF PSYCHOTIC DISORDER, WITH POSTPARTUM ONSET Ballismus Behaviour disorder Bipolar I disorder Bipolar II disorder Bipolar disorder Blood prolactin abnormal Borderline personality disorder Brain abscess Brain injury Brain neoplasm Brain oedema Brain stem glioma Breath holding Brief psychotic disorder, with postpartum onset CANCER PAIN CARDIAC DISORDER CARDIAC OPERATION CARDIO-RESPIRATORY ARREST CARDIOVASCULAR EVENT PROPHYLAXIS CATAPLEXY CATATONIA CDKL5 deficiency disorder CENTRAL NERVOUS SYSTEM NEOPLASM CEREBELLAR ATAXIA CEREBELLAR INFARCTION CEREBRAL AMYLOID ANGIOPATHY CEREBRAL DISORDER CEREBRAL HAEMATOMA CEREBRAL HAEMORRHAGE CEREBRAL INFARCTION CEREBRAL ISCHAEMIA CEREBRAL PALSY CEREBRAL SARCOIDOSIS CEREBRAL TOXOPLASMOSIS CEREBROVASCULAR ACCIDENT CHARLES BONNET SYNDROME CHEMOTHERAPY CHILDHOOD PSYCHOSIS CHOREA CHOREOATHETOSIS CHRONIC INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY CHRONIC MYELOMONOCYTIC LEUKAEMIA CLONIC CONVULSION CLONUS CLUSTER HEADACHE COELIAC DISEASE COGNITIVE DISORDER COLON CANCER STAGE IV COMPLETED SUICIDE COMPLEX PARTIAL SEIZURES COMPULSIVE SHOPPING CONDITION AGGRAVATED CONDUCT DISORDER CONFUSIONAL STATE CONGENITAL RETINOBLASTOMA CONSTRICTED AFFECT CONVERSION DISORDER CONVULSION CONVULSION NEONATAL CONVULSION PROPHYLAXIS CORTICAL DYSPLASIA CRANIAL OPERATION CRANIOCEREBRAL INJURY CRANIOPHARYNGIOMA CSWS SYNDROME CSWS syndrome CUTANEOUS T-CELL LYMPHOMA CUTIS VERTICIS GYRATA CYCLOTHYMIC DISORDER Cardiac failure Cataplexy Catatonia Cerebral amyloid angiopathy Cerebral disorder Cerebral palsy Chemotherapy Childhood psychosis Chorea Chorea-acanthocytosis Chronic kidney disease Chronic paroxysmal hemicrania Clonic convulsion Clonus Cluster headache Coeliac disease Cognitive disorder Coma Completed suicide Confusional state Congenital multiplex arthrogryposis Consciousness fluctuating Conversion disorder Convulsions local Cortical dysplasia Craniocerebral injury Cyanosis Cyclic vomiting syndrome Cytogenetic abnormality DEDIFFERENTIATED LIPOSARCOMA DELIRIUM DELUSION DELUSION OF REFERENCE DELUSIONAL DISORDER, PERSECUTORY TYPE DELUSIONAL DISORDER, UNSPECIFIED TYPE DEMENTIA DEMENTIA ALZHEIMER'S TYPE DEMENTIA ALZHEIMER^S TYPE DEMENTIA WITH LEWY BODIES DEMYELINATION DEPENDENCE DEPRESSED MOOD DEPRESSION DEPRESSIVE SYMPTOM DEVELOPMENTAL DELAY DIABETES MELLITUS DIABETIC NEUROPATHY DIARRHOEA DISEASE RECURRENCE DISRUPTIVE MOOD DYSREGULATION DISORDER DISSOCIATION DISSOCIATIVE DISORDER DISTRACTIBILITY DISTURBANCE IN ATTENTION DISTURBANCE IN SOCIAL BEHAVIOUR DIZZINESS DOPAMINE DYSREGULATION SYNDROME DROP ATTACKS DRUG ABUSE DRUG ABUSER DRUG ADMINISTRATION ERROR DRUG DEPENDENCE DRUG DISPENSING ERROR DRUG EXPOSURE DURING PREGNANCY DRUG EXPOSURE IN UTERO DRUG EXPOSURE VIA BREAST MILK DRUG RESISTANCE DRUG THERAPY DRUG USE FOR UNKNOWN INDICATION DRUG WITHDRAWAL SYNDROME DYSKINESIA DYSMORPHISM DYSPHAGIA DYSPHORIA DYSPLASIA DYSTHYMIC DISORDER DYSTONIA Defiant behaviour Delayed sleep phase Delirium Delirium tremens Delusion Delusion of grandeur Delusion of replacement Delusional disorder, persecutory type Delusional disorder, unspecified type Dementia Dementia Alzheimer^s type Dementia of the Alzheimer^s type, uncomplicated Dementia with Lewy bodies Depression Depressive symptom Developmental delay Diffuse axonal injury Disease complication Disorientation Disruptive mood dysregulation disorder Dissociative disorder Disturbance in social behaviour Dizziness Drop attacks Drug abuse Drug dependence Drug ineffective for unapproved indication Drug therapy Drug withdrawal maintenance therapy Drug withdrawal syndrome Dysarthria Dyskinesia Dyspnoea Dystonia EARLY INFANTILE EPILEPTIC ENCEPHALOPATHY WITH BURST-SUPPRESSION ELECTROCARDIOGRAM ABNORMAL ELECTROENCEPHALOGRAM ELECTROENCEPHALOGRAM ABNORMAL ELECTROLYTE IMBALANCE EMOTIONAL DISORDER ENCEPHALITIS ENCEPHALITIS AUTOIMMUNE ENCEPHALOPATHY ENCEPHALOPATHY NEONATAL EPILEPSY EPILEPSY CONGENITAL EPILEPSY WITH MYOCLONIC-ATONIC SEIZURES EPILEPTIC ENCEPHALOPATHY EPILEPTIC SEIZURE ERYTHROLEUKAEMIA EUPHORIC MOOD EXPOSURE DURING PREGNANCY EXTRADURAL HAEMATOMA EXTRAPYRAMIDAL DISORDER EYE DISORDER EYELID MYOCLONUS Early infantile epileptic encephalopathy with burst-suppression Eclampsia Electroencephalogram abnormal Emotional disorder Encephalitis Encephalitis Japanese B Encephalitis autoimmune Encephalitis herpes Encephalitis viral Encephalopathy Epilepsia partialis continua Epilepsy Epilepsy congenital Epilepsy of infancy with migrating focal seizures Epilepsy with myoclonic-atonic seizures Epileptic encephalopathy Epileptic psychosis Epstein-Barr virus infection Essential tremor Euphoric mood Evidence based treatment Exposure during pregnancy Extragonadal primary seminoma (pure) Extrapyramidal disorder Eyelid myoclonus FACIAL NEURALGIA FALL FAMILIAL RISK FACTOR FEBRILE CONVULSION FEBRILE INFECTION FEBRILE INFECTION-RELATED EPILEPSY SYNDROME FEELING ABNORMAL FIBROMYALGIA FLIGHT OF IDEAS FOCAL DYSCOGNITIVE SEIZURES FOCAL EPILEPSY FOETAL ALCOHOL SYNDROME FOETAL EXPOSURE DURING PREGNANCY FRAGILE X SYNDROME FRONTAL LOBE EPILEPSY Facial pain Faciobrachial dystonic seizure Fall Febrile convulsion Febrile infection-related epilepsy syndrome Fibromyalgia Focal dyscognitive seizures Foetal exposure during pregnancy Foetal exposure timing unspecified Frontal lobe epilepsy GAIT DISTURBANCE GASTROINTESTINAL DISORDER GELASTIC SEIZURE GENERALISED ANXIETY DISORDER GENERALISED NON-CONVULSIVE EPILEPSY GENERALISED TONIC-CLONIC SEIZURE GLAUCOMA GLIOBLASTOMA GLIOBLASTOMA MULTIFORME GLIOMA GLIOMATOSIS CEREBRI GRAND MAL CONVULSION GRIEF REACTION Galactosialidosis Gambling disorder Ganglioneuroma Gastric ulcer Gastritis bacterial Gaucher^s disease Gaucher^s disease type II Gaucher^s disease type III Gelastic seizure Gene mutation Generalised anxiety disorder Generalised onset non-motor seizure Generalised tonic-clonic seizure Glioblastoma Glioblastoma multiforme Glioma Glioneuronal tumour Gliosis Glomerulonephritis rapidly progressive Glossopharyngeal neuralgia Gout Grey matter heterotopia HAEMANGIOMA HALLUCINATION HALLUCINATION, AUDITORY HALLUCINATION, VISUAL HEAD DISCOMFORT HEAD INJURY HEADACHE HEMICONVULSION-HEMIPLEGIA-EPILEPSY SYNDROME HEMIPARESIS HEMIPLEGIA HEMIPLEGIC MIGRAINE HEPATITIS C HEPATO-LENTICULAR DEGENERATION HEPATOCELLULAR CARCINOMA HEREDITARY ATAXIA HERPES SIMPLEX ENCEPHALITIS HISTRIONIC PERSONALITY DISORDER HIV INFECTION HIV-associated neurocognitive disorder HODGKIN'S DISEASE NODULAR SCLEROSIS STAGE UNSPECIFIED HUNTINGTON'S CHOREA HUNTINGTON^S DISEASE HYDROCEPHALUS HYPERAMMONAEMIA HYPERAMMONAEMIC ENCEPHALOPATHY HYPERGLYCAEMIA HYPERGLYCAEMIC SEIZURE HYPERGLYCINAEMIA HYPERHIDROSIS HYPERKINESIA HYPERSEXUALITY HYPERTENSION HYPOAESTHESIA HYPOGLYCAEMIA HYPOMANIA HYPOTHYROIDISM HYPOXIC-ISCHAEMIC ENCEPHALOPATHY HYPOXIC-ISCHEMIC ENCEPHALOPATHY Haematological malignancy Haemorrhage Hallucination, auditory Hallucinations, mixed Headache Hemiparesis Hereditary ataxia Hereditary neuropathic amyloidosis Hiccups Holmes tremor Huntington^s disease Hyperkinesia Hyperoxaluria Hypersensitivity Hypersomnia Hypertonia Hypomania Hypothalamic hamartoma Hypothyroidism Hypoxic-ischaemic encephalopathy IDEAS OF REFERENCE IDIOPATHIC GENERALISED EPILEPSY ILL-DEFINED DISORDER ILLNESS ANXIETY DISORDER IMPAIRED REASONING IMPULSE-CONTROL DISORDER IMPULSIVE BEHAVIOUR INAPPROPRIATE AFFECT INFANTILE SPASMS INFARCTION INFECTION INJURY INSOMNIA INTELLECTUAL DISABILITY INTENTIONAL DRUG MISUSE INTENTIONAL MISUSE INTENTIONAL OVERDOSE INTENTIONAL PRODUCT MISUSE INTENTIONAL SELF-INJURY INTERMITTENT EXPLOSIVE DISORDER INTERSTITIAL LUNG DISEASE INTRACRANIAL INJURY INTRACRANIAL PRESSURE INCREASED IRRITABILITY ISODICENTRIC CHROMOSOME 15 SYNDROME Idiopathic generalised epilepsy Ill-defined disorder Illness Immune-mediated encephalitis Immunosuppression Imprisonment Impulsive behaviour Inappropriate affect Infantile spasms Infection Inflammatory bowel disease Influenza Insomnia Intellectual disability Intensive care unit delirium Intentional overdose Intentional product misuse Intentional self-injury Intermittent explosive disorder Irritability Ischaemic stroke Isodicentric chromosome 15 syndrome JEALOUS DELUSION JUVENILE ABSENCE EPILEPSY JUVENILE MYOCLONIC EPILEPSY Jeavons syndrome Joint contracture Judgement impaired Juvenile absence epilepsy Juvenile myoclonic epilepsy KAPOSI'S SARCOMA KLINEFELTER^S SYNDROME Krabbe^s disease LAFORA^S MYOCLONIC EPILEPSY LEARNING DISORDER LEIOMYOSARCOMA LEIOMYOSARCOMA METASTATIC LENNOX--GASTAUT SYNDROME LENNOX-GASTAUT SYNDROME LEUKAEMIA RECURRENT LEUKOCYTOSIS LEUKODYSTROPHY LIMBIC ENCEPHALITIS LIVER DISORDER LIVER INJURY LOGORRHOEA LOSS OF CONSCIOUSNESS LUNG INFECTION LUNG NEOPLASM MALIGNANT LYMPHOCYTIC LEUKAEMIA Lafora^s myoclonic epilepsy Lennox-Gastaut syndrome Leptospirosis Limbic encephalitis Liver transplant Logorrhoea Loss of consciousness MAINTENANCE OF ANAESTHESIA MAJOR DEPRESSION MALAISE MALIGNANT FIBROUS HISTIOCYTOMA MANIA MANIC SYMPTOM MATERNAL DRUGS AFFECTING FOETUS MATERNAL EXPOSURE DURING PREGNANCY MATERNAL EXPOSURE TIMING UNSPECIFIED MEDICATION ERROR MEDULLOBLASTOMA MEDULLOBLASTOMA RECURRENT MELAS syndrome MEMORY IMPAIRMENT MENINGIOMA MENINGITIS MENINGOENCEPHALITIS HERPETIC MENINGORRHAGIA MENTAL DISORDER MENTAL IMPAIRMENT MENTAL RETARDATION MENTAL STATUS CHANGES METASTASES TO CENTRAL NERVOUS SYSTEM METASTASIS METASTATIC MALIGNANT MELANOMA METASTATIC NEOPLASM METASTATIC OCULAR MELANOMA METASTATIC RENAL CELL CARCINOMA MICROCEPHALY MIDDLE INSOMNIA MIGRAINE MIGRAINE PROPHYLAXIS MIGRAINE WITH AURA MIGRAINE WITHOUT AURA MILD MENTAL RETARDATION MOOD ALTERED MOOD DISORDER DUE TO A GENERAL MEDICAL CONDITION MOOD SWINGS MOROSE MOSAICISM MOVEMENT DISORDER MUCOSAL DRYNESS MULTIPLE DRUG OVERDOSE INTENTIONAL MULTIPLE INJURIES MULTIPLE MYELOMA MULTIPLE SCLEROSIS MUSCLE SPASMS MUSCLE SPASTICITY MUSCLE TWITCHING MUSCULOSKELETAL STIFFNESS MYELODYSPLASTIC SYNDROME MYELOID LEUKAEMIA MYOCLONIC EPILEPSY MYOCLONIC EPILEPSY AND RAGGED-RED FIBERS MYOCLONUS Maintenance of anaesthesia Major depression Malignant catatonia Mania Manic symptom Maternal drugs affecting foetus Maternal exposure during pregnancy Maternal exposure timing unspecified Medication error Medulloblastoma Medulloblastoma recurrent Mental disorder Mental impairment Mental status changes Metastases to bone marrow Metastatic neoplasm Microcephaly Migraine Migraine prophylaxis Migraine without aura Mitochondrial DNA mutation Mixed anxiety and depressive disorder Mood altered Mood swings Movement disorder Muscle spasms Muscle twitching Musculoskeletal stiffness Myoclonic dystonia Myoclonic epilepsy Myoclonic epilepsy and ragged-red fibres Myoclonus NASOPHARYNGEAL CANCER NEGATIVE THOUGHTS NEGATIVISM NEONATAL ASPHYXIA NEONATAL SEIZURE NEOPLASM NEOPLASM MALIGNANT NEOPLASM PROGRESSION NERVOUS SYSTEM DISORDER NERVOUSNESS NEURALGIA NEUROCYSTICERCOSIS NEUROENDOCRINE TUMOUR NEUROLEPTIC MALIGNANT SYNDROME NEUROLOGICAL SYMPTOM NEUROMYOTONIA NEURONAL CEROID LIPOFUSCINOSIS NEUROPATHY PERIPHERAL NEUROPSYCHIATRIC SYMPTOMS NEUROPSYCHIATRIC SYNDROME NON-SMALL CELL LUNG CANCER Negative thoughts Negativism Neonatal epileptic seizure Neonatal seizure Neoplasm Neoplasm malignant Nervous system disorder Neuralgia Neurodevelopmental disorder Neuroleptic malignant syndrome Neuronal ceroid lipofuscinosis Neuropathy peripheral Neuropsychiatric lupus Neuropsychiatric symptoms Neuropsychological symptoms Neurosyphilis New daily persistent headache New onset refractory status epilepticus OBSESSIVE THOUGHTS OBSESSIVE-COMPULSIVE DISORDER OCCIPITAL NEURALGIA OCULAR CANCER METASTATIC OFF LABEL USE OPPOSITIONAL DEFIANT DISORDER OPSOCLONUS MYOCLONUS ORAL HERPES OROPHARYNGEAL PAIN OSTEOARTHRITIS OSTEOSARCOMA METASTATIC OVARIAN CANCER OVARIAN CANCER METASTATIC OVERDOSE Obsessive-compulsive disorder Obsessive-compulsive personality disorder Obstructive sleep apnoea syndrome Occipital lobe epilepsy Oculocephalogyric reflex absent Ophthalmoplegia Optic atrophy Orthostatic headache Orthostatic tremor Overdose Overweight PAIN PAIN MANAGEMENT PAIN PROPHYLAXIS PALLIATIVE CARE PANIC ATTACK PANIC DISORDER PARALYSIS PARANOIA PARKINSON'S DISEASE PARKINSON^S DISEASE PARTIAL SEIZURES PARTIAL SEIZURES WITH SECONDARY GENERALISATION PATERNAL DRUGS AFFECTING FOETUS PATERNAL EXPOSURE TIMING UNSPECIFIED PCDH19 gene-related epilepsy PERIPHERAL ARTERIAL OCCLUSIVE DISEASE PERIPHERAL SENSORY NEUROPATHY PERSECUTORY DELUSION PERSISTENT GENITAL AROUSAL DISORDER PERSONALITY DISORDER PETIT MAL EPILEPSY PHELAN-MCDERMID SYNDROME PNEUMONIA POISONING POISONING DELIBERATE POLYDIPSIA POST CONCUSSION SYNDROME POST PROCEDURAL HAEMATOMA POST STROKE EPILEPSY POST STROKE SEIZURE POST-ANOXIC MYOCLONUS POST-TRAUMATIC EPILEPSY POST-TRAUMATIC STRESS DISORDER POSTOPERATIVE CARE POSTPARTUM DEPRESSION PRADER-WILLI SYNDROME PRE-EXISTING DISEASE PREGNANCY PREMEDICATION PRESCRIPTION DRUG USED WITHOUT A PRESCRIPTION PRODUCT ADMINISTRATION ERROR PRODUCT USE IN UNAPPROVED INDICATION PRODUCT USED FOR UNKNOWN INDICATION PROFOUND MENTAL RETARDATION PROPHYLAXIS PROSTATE CANCER PROSTATE CANCER METASTATIC PRURITUS PSYCHIATRIC DISORDER NOS PSYCHIATRIC SYMPTOM PSYCHOGENIC SEIZURE PSYCHOMOTOR HYPERACTIVITY PSYCHOMOTOR RETARDATION PSYCHOMOTOR SEIZURES PSYCHOTHERAPY PSYCHOTIC BEHAVIOUR PSYCHOTIC DISORDER PSYCHOTIC DISORDER DUE TO A GENERAL MEDICAL CONDITION PSYCHOTIC SYMPTOM Pain Pain in extremity Pain management Painful ejaculation Panic attack Paradoxical drug reaction Paraesthesia Paranoia Parietal lobe epilepsy Parkinson^s disease Parkinsonism Paroxysmal sympathetic hyperactivity Partial seizures Partial seizures with secondary generalisation Persistent depressive disorder Personality disorder Petit mal epilepsy Phelan-McDermid syndrome Pneumonia aspiration Pneumonia bacterial Poisoning Poisoning deliberate Polyneuropathy Post lumbar puncture syndrome Post stroke epilepsy Post-anoxic myoclonus Post-traumatic epilepsy Post-traumatic stress disorder Posterior reversible encephalopathy syndrome Postictal paralysis Prader-Willi syndrome Pre-existing disease Product administration error Product use in unapproved indication Product used for unknown indication Prophylaxis Prophylaxis against transplant rejection Psoriatic arthropathy Psychiatric care Psychiatric decompensation Psychiatric disorder prophylaxis Psychiatric evaluation Psychiatric symptom Psychogenic seizure Psychomotor hyperactivity Psychosocial support Psychotherapy Psychotic behaviour Psychotic disorder Psychotic disorder due to a general medical condition Psychotic symptom Pudendal canal syndrome QUADRIPARESIS QUADRIPLEGIA Quadriplegia RASMUSSEN ENCEPHALITIS RECTAL CANCER METASTATIC RECTAL CANCER STAGE IV REFRACTORY ANAEMIA WITH RINGED SIDEROBLASTS RELAPSING-REMITTING MULTIPLE SCLEROSIS RENAL CELL CARCINOMA RENAL CELL CARCINOMA STAGE IV RENAL TRANSPLANT RESTLESS LEGS SYNDROME RESTLESSNESS RETINITIS PIGMENTOSA RETINOBLASTOMA RETT^S DISORDER REVERSIBLE POSTERIOR LEUKOENCEPHALOPATHY SYNDROME ROAD TRAFFIC ACCIDENT Rash Rasmussen encephalitis Reactive attachment disorder Rebound effect Renal cancer metastatic Respiratory failure Restlessness Rett syndrome Reversal of sedation Rhabdoid tumour of the kidney SALVAGE THERAPY SARCOIDOSIS SARCOMA SARCOMA METASTATIC SCHIZOAFFECTIVE DISORDER SCHIZOAFFECTIVE DISORDER BIPOLAR TYPE SCHIZOAFFECTIVE DISORDER DEPRESSIVE TYPE SCHIZOPHRENIA SCHIZOPHRENIA, CATATONIC TYPE SCHIZOPHRENIA, DISORGANISED TYPE SCHIZOPHRENIA, PARANOID TYPE SCHIZOPHRENIA, UNDIFFERENTIATED TYPE SCHIZOPHRENIFORM DISORDER SCREAMING SEASONAL AFFECTIVE DISORDER SEDATION SEDATIVE THERAPY SEIZURE SEIZURE CLUSTER SEIZURE PROPHYLAXIS SEIZURES SELF INJURIOUS BEHAVIOUR SENILE PSYCHOSIS SEVERE MENTAL RETARDATION SEVERE MYOCLONIC EPILEPSY OF INFANCY SIMPLE PARTIAL SEIZURES SLEEP DISORDER SLEEP DISORDER THERAPY SOCIAL AVOIDANT BEHAVIOUR SOMNAMBULISM SOMNOLENCE SPEECH DISORDER SPINAL MUSCULAR ATROPHY SPINOCEREBELLAR DISORDER STAPHYLOCOCCAL INFECTION STATUS EPILEPTICUS STATUS MIGRAINOSUS STIFF PERSON SYNDROME STRABISMUS STRESS SUBACUTE SCLEROSING PANENCEPHALITIS SUBDURAL HAEMATOMA SUBSTANCE USE DISORDER SUBSTANCE-INDUCED PSYCHOTIC DISORDER SUFFOCATION FEELING SUICIDAL BEHAVIOUR SUICIDAL IDEATION SUICIDE ATTEMPT SUNCT SYNDROME SUNCT syndrome SUPPORTIVE CARE SURGERY SUSPECTED SUICIDE SYDENHAM'S CHOREA SYDENHAM^S CHOREA SYNCOPE SYNOVIAL SARCOMA METASTATIC SYSTEMIC LUPUS ERYTHEMATOSUS Salivary hypersecretion Schizoaffective disorder Schizoaffective disorder bipolar type Schizoaffective disorder depressive type Schizophrenia Schizophreniform disorder Schizotypal personality disorder Sedation Sedative therapy Seizure Seizure cluster Seizure prophylaxis Self-injurious ideation Senile dementia Severe myoclonic epilepsy of infancy Sexually inappropriate behaviour Shock Simple partial seizures Sleep disorder Sleep disorder therapy Sleep related hypermotor epilepsy Social anxiety disorder Social avoidant behaviour Somnolence Spinal muscular atrophy Status epilepticus Status migrainosus Stevens-Johnson syndrome Stiff person syndrome Strabismus Stress Subarachnoid haemorrhage Subdural haematoma Substance use disorder Substance-induced mood disorder Substance-induced psychotic disorder Suicidal behaviour Suicidal ideation Suicide attempt Suspected suicide Sydenham^s chorea Syncope TACHYCARDIA TARDIVE DYSKINESIA TEMPORAL LOBE EPILEPSY TENSION TENSION HEADACHE THERAPEUTIC PROCEDURE THINKING ABNORMAL THROMBOTIC MICROANGIOPATHY THYMUS DISORDER TIC TONIC CONVULSION TORTICOLLIS TOURETTE'S DISORDER TOURETTE^S DISORDER TOXIC ENCEPHALOPATHY TOXICITY TO VARIOUS AGENTS TRAUMATIC BRAIN INJURY TRAUMATIC DELIVERY TRAUMATIC INTRACRANIAL HAEMORRHAGE TREMOR TRIGEMINAL NEURALGIA TRISOMY 13 TRISOMY 21 TUBERCULOMA OF CENTRAL NERVOUS SYSTEM TUBEROUS SCLEROSIS COMPLEX Tachycardia Tardive dyskinesia Temporal lobe epilepsy Therapeutic procedure Therapy cessation Tic Tonic clonic movements Tonic convulsion Tonic posturing Tourette^s disorder Toxicity to various agents Treatment noncompliance Tremor Trigeminal neuralgia Trisomy 21 Tuberous sclerosis complex Typical aura without headache UNEVALUABLE EVENT URINARY TRACT INFECTION VASCULAR DEMENTIA VERTIGO VISUAL IMPAIRMENT Vascular dementia Venous thrombosis Ventricular septal defect Vertigo CNS origin WEIGHT INCREASED WRONG DRUG ADMINISTERED WRONG PRODUCT ADMINISTERED Withdrawal syndrome Wrong patient Wrong patient received product Valproic brand names and reporting trend
Valproic is sold under the brand name Depakene.
Quarterly reports (2004–2025) An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
Taking valproic with another medication? Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.
