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Vaborbactam Side Effects

The most commonly reported side effects of vaborbactam include off label use, drug ineffective for unapproved indication, and pathogen resistance, based on 74 FDA adverse event reports from 2018 to 2025. 4.1% of reports found the drug to be ineffective.

Vaborbactam side effects

Percentages show how often each reaction appears relative to total reports for vaborbactam.

1
Off Label Use31.1%23
2
Drug Ineffective For Unapproved Indication10.8%8
3
Pathogen Resistance9.5%7
4
Alanine Aminotransferase Increased8.1%6
5
Nausea8.1%6
6
Death6.8%5
7
Rash6.8%5
8
Cystic Fibrosis6.8%5
9
Headache5.4%4
10
Seizure5.4%4
11
Hypersensitivity4.1%3
12
Erythema4.1%3
13
Product Use In Unapproved Indication4.1%3
14
Drug Resistance4.1%3
15
Condition Aggravated4.1%3

These are voluntary reports and do not establish that vaborbactam caused these reactions.

Report severity

70.3%Serious52 reports
25.7%Hospitalizations19 reports
14.9%Fatal11 reports

Seriousness is determined by the reporter, not by OpenClaim.

Vaborbactam drug interactions

Other drugs that appear in adverse event reports alongside vaborbactam. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Meropenem81.1%60
2
Linezolid20.3%15
3
Amikacin-sulfate12.2%9
4
Clofazimine10.8%8
5
Bedaquiline-fumarate9.5%7
6
Daptomycin9.5%7
7
Levofloxacin8.1%6
8
Imipenem4.1%3
9
Tigecycline4.1%3
10
Gentamicin-sulfate2.7%2
11
Ceftolozane-sulfate2.7%2
12
Tazobactam-sodium2.7%2
13
Minocycline-hydrochloride2.7%2
14
Eravacycline-dihydrochloride2.7%2
15
Tedizolid-phosphate2.7%2

Taken alongside

1
Meropenem13.5%10
2
Tigecycline9.5%7
3
Pantoprazole-sodium8.1%6
4
Albuterol8.1%6
5
Insulin8.1%6
6
Furosemide8.1%6
7
Dexamethasone8.1%6
8
Voriconazole6.8%5
9
Vancomycin5.4%4
10
Imipenem5.4%4
11
Diphenhydramine5.4%4
12
Chlorhexidine-gluconate5.4%4
13
Azithromycin5.4%4
14
Amlodipine5.4%4
15
Prednisone5.4%4

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports vaborbactam side effects

43.2% of vaborbactam adverse event reports involve female patients and 28.4% involve male patients. The largest age group is adult at 73%. These figures reflect who reports side effects, not underlying risk.

Sex

Female43.2%
Male28.4%
Unknown28.4%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6473.5%
65+26.5%

What is vaborbactam used for

Conditions and purposes for which patients were taking vaborbactam when the adverse event was reported.

Abdominal AbscessAchromobacter InfectionBacterial InfectionBronchopulmonary AspergillosisBurkholderia Cepacia Complex InfectionBacteraemiaCentral Nervous System InfectionCerebral CystCns VentriculitisCns VentriculitisCystic FibrosisCitrobacter InfectionCystic FibrosisEnterobacter InfectionEscherichia Peritonitis

Showing 15 of 42 indications

Vaborbactam brand names and reporting trend

Vaborbactam is sold under the brand name Vabomere.

Brand names

Vabomere28

Quarterly reports (20182025)

201820202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking vaborbactam with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.