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Urofollitropin Side Effects

The most commonly reported side effects of urofollitropin include ovarian hyperstimulation syndrome, abdominal distension, and abdominal pain, based on 276 FDA adverse event reports from 2004 to 2025. 19.9% of reports found the drug to be ineffective.

Urofollitropin side effects

Percentages show how often each reaction appears relative to total reports for urofollitropin.

1
Ovarian Hyperstimulation Syndrome22.1%61
2
Drug Ineffective19.9%55
3
Abdominal Distension9.1%25
4
Abdominal Pain7.6%21
5
Diarrhoea6.2%17
6
Nausea6.2%17
7
Ovarian Hyperstimulation Syndrome5.8%16
8
Drug Exposure During Pregnancy4.3%12
9
Pain4.3%12
10
Pyrexia4.0%11
11
Vomiting4.0%11
12
Anaemia3.6%10
13
Chest Discomfort3.6%10
14
Ectopic Pregnancy3.3%9
15
Abdominal Discomfort3.3%9

These are voluntary reports and do not establish that urofollitropin caused these reactions.

Report severity

67.8%Serious187 reports
47.8%Hospitalizations132 reports
2.5%Fatal7 reports

Seriousness is determined by the reporter, not by OpenClaim.

Urofollitropin drug interactions

Other drugs that appear in adverse event reports alongside urofollitropin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Menotropins-fsh22.1%61
2
Gonadotropin-chorionic15.9%44
3
Progesterone13.8%38
4
Follitropin-alfa-beta9.8%27
5
Choriogonadotropin-alfa8.0%22
6
Estradiol5.4%15
7
Leuprolide5.1%14
8
Triptorelin-pamoate4.7%13
9
Clomiphene-citrate4.0%11
10
Prednisone3.6%10
11
Cetrorelix-acetate3.3%9
12
Vedolizumab2.9%8
13
Levofloxacin2.9%8
14
Mesalamine2.9%8
15
Letrozole2.5%7

Taken alongside

1
Sodium-chloride11.6%32
2
Menotropins-fsh10.1%28
3
Progesterone5.8%16
4
Leuprolide3.6%10
5
Folic-acid2.9%8
6
Scopolamine2.9%8
7
Buspirone-hydrochloride2.9%8
8
Methotrexate2.9%8
9
Cabergoline2.5%7
10
Acetaminophen2.5%7
11
Cetrorelix-acetate2.5%7
12
Insulin2.5%7
13
Bupropion2.5%7
14
Atorvastatin-calcium2.5%7
15
Naproxen2.2%6

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports urofollitropin side effects

85.9% of urofollitropin adverse event reports involve female patients and 8.7% involve male patients. The largest age group is adult at 89%. These figures reflect who reports side effects, not underlying risk.

Sex

Female85.9%
Male8.7%
Unknown5.4%

Age group

< 25.1%
2–110.0%
12–170.0%
18–6489.2%
65+5.6%

What is urofollitropin used for

Conditions and purposes for which patients were taking urofollitropin when the adverse event was reported.

Antibiotic TherapyArtificial Insemination By PartnerAssisted FertilisationArtificial InseminationAssisted Reproductive TechnologyControlled Ovarian StimulationDrug Use For Unknown IndicationHormone Replacement TherapyHypertensionHypertensionIn Vitro FertilisationInfertilityInfertility FemaleIn Vitro FertilisationInfertility

Showing 15 of 28 indications

Urofollitropin brand names and reporting trend

Urofollitropin is sold under the brand name Bravelle.

Brand names

Bravelle171

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking urofollitropin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.