OpenClaim

Uridine Side Effects

The most commonly reported side effects of uridine include diarrhoea, vomiting, and nausea, based on 295 FDA adverse event reports from 2004 to 2025.

Uridine side effects

Percentages show how often each reaction appears relative to total reports for uridine.

1
Diarrhoea9.2%27
2
Vomiting6.8%20
3
Nausea6.8%20
4
Complication Associated With Device6.8%20
5
Thrombocytopenia5.8%17
6
Neutropenia5.4%16
7
Off Label Use5.1%15
8
Decreased Appetite4.1%12
9
Asthenia4.1%12
10
Pyrexia4.1%12
11
Mucosal Inflammation3.7%11
12
Pneumonia3.1%9
13
Death3.1%9
14
Hypokalaemia3.1%9
15
Inappropriate Schedule Of Product Administration2.7%8

These are voluntary reports and do not establish that uridine caused these reactions.

Report severity

73.6%Serious217 reports
49.2%Hospitalizations145 reports
15.6%Fatal46 reports

Seriousness is determined by the reporter, not by OpenClaim.

Uridine drug interactions

Other drugs that appear in adverse event reports alongside uridine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Capecitabine7.8%23
2
Aprepitant5.8%17
3
Fosaprepitant-dimeglumine5.8%17
4
Fluorouracil4.4%13
5
Atezolizumab2.7%8
6
Ritonavir2.4%7
7
Trastuzumab2.4%7
8
Oxaliplatin2.4%7
9
Lenvatinib-mesylate2.0%6
10
Prednisolone1.7%5
11
Ribavirin1.4%4
12
Risedronate-sodium1.4%4
13
Paclitaxel1.4%4
14
Cisplatin1.4%4
15
Gemcitabine1.4%4

Taken alongside

1
Acetaminophen9.2%27
2
Fluorouracil8.8%26
3
Furosemide8.1%24
4
Dexamethasone7.8%23
5
Palonosetron-hydrochloride5.8%17
6
Oxycodone5.4%16
7
Aspirin5.4%16
8
Amlodipine4.7%14
9
Capecitabine4.7%14
10
Magnesium-oxide4.1%12
11
Naloxone-hydrochloride4.1%12
12
Esomeprazole4.1%12
13
Lactulose4.1%12
14
Megestrol-acetate3.7%11
15
Tramadol-hydrochloride3.7%11

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports uridine side effects

47.8% of uridine adverse event reports involve female patients and 46.4% involve male patients. The largest age group is adult at 52%. These figures reflect who reports side effects, not underlying risk.

Sex

Female47.8%
Male46.4%
Unknown5.8%

Age group

< 22.7%
2–112.7%
12–171.2%
18–6451.5%
65+41.9%

What is uridine used for

Conditions and purposes for which patients were taking uridine when the adverse event was reported.

Accidental Exposure To ProductAccidental OverdoseAcquired Pyrimidine Metabolism DisorderAdverse Drug ReactionAntacid TherapyArthropod BiteBacterial InfectionBronchitisCerebral InfarctionChemotherapy Toxicity AttenuationCongenital Disorder Of GlycosylationCytogenetic AbnormalityChemotherapy Toxicity AttenuationDementiaDermatitis Acneiform

Showing 15 of 62 indications

Uridine brand names and reporting trend

Uridine is sold under the brand name Xuriden.

Brand names

Xuriden34

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking uridine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.