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Tyrosine Side Effects

The most commonly reported side effects of tyrosine include weight decreased, diarrhoea, and nausea, based on 2,708 FDA adverse event reports from 2004 to 2025. 4.7% of reports found the drug to be ineffective.

Tyrosine side effects

Percentages show how often each reaction appears relative to total reports for tyrosine.

1
Weight Decreased9.3%253
2
Diarrhoea8.4%228
3
Nausea7.5%203
4
Weight Increased6.9%188
5
Fatigue6.5%175
6
Abdominal Pain6.0%163
7
Vomiting6.0%162
8
Decreased Appetite6.0%162
9
Product Dose Omission Issue6.0%162
10
Drug Ineffective4.7%127
11
Pyrexia4.7%126
12
Vascular Device Infection4.6%124
13
Dehydration4.3%117
14
Abdominal Distension4.2%115
15
Headache4.0%109

These are voluntary reports and do not establish that tyrosine caused these reactions.

Report severity

79.0%Serious2,138 reports
47.2%Hospitalizations1,277 reports
13.1%Fatal354 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tyrosine drug interactions

Other drugs that appear in adverse event reports alongside tyrosine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Teduglutide24.0%649
2
Pyridoxine9.9%268
3
Niacinamide9.6%260
4
Adalimumab4.5%121
5
Sodium-oxybate3.2%87
6
Pegvaliase-pqpz3.2%87
7
Infliximab3.0%81
8
Sapropterin-dihydrochloride1.2%32
9
Prednisone1.1%29
10
Vedolizumab1.1%29
11
Cyclophosphamide1.0%28
12
Acetaminophen1.0%28
13
Doxorubicin-hydrochloride1.0%28
14
Fentanyl1.0%26
15
Omeprazole1.0%26

Taken alongside

1
Pyridoxine67.1%1,817
2
Niacinamide66.8%1,810
3
Ergocalciferol18.2%494
4
Acetaminophen14.6%396
5
Pantoprazole-sodium11.6%313
6
Loperamide-hydrochloride10.8%293
7
Ondansetron10.6%286
8
Omeprazole9.2%249
9
Furosemide8.9%241
10
Cyanocobalamin8.1%218
11
Lorazepam7.8%210
12
Vancomycin7.4%200
13
Levothyroxine-sodium7.2%196
14
Buspirone-hydrochloride6.9%186
15
Sodium-chloride6.7%181

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tyrosine side effects

54.1% of tyrosine adverse event reports involve female patients and 38.1% involve male patients. The largest age group is adult at 58%. These figures reflect who reports side effects, not underlying risk.

Sex

Female54.1%
Male38.1%
Unknown7.8%

Age group

< 25.7%
2–118.4%
12–174.2%
18–6458.5%
65+23.2%

What is tyrosine used for

Conditions and purposes for which patients were taking tyrosine when the adverse event was reported.

Abdominal PainAcute Graft Versus Host DiseaseAcute Lymphocytic LeukaemiaAcute Myeloid LeukaemiaAffective DisorderAnaemiaAnorexiaAnxietyArthropathyAtrial FibrillationAttention Deficit/hyperactivity DisorderAttention Deficit Hyperactivity DisorderAutoimmune ThyroiditisBlood Pressure AbnormalBreast Cancer Metastatic

Showing 15 of 145 indications

Tyrosine brand names and reporting trend

Tyrosine is sold under the brand name Tpn.

Brand names

Tpn683

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tyrosine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.