OpenClaim

Tyloxapol Side Effects

The most commonly reported side effects of tyloxapol include diarrhoea, thrombocytopenia, and liver function test increased, based on 17 FDA adverse event reports from 2004 to 2024.

Tyloxapol side effects

Percentages show how often each reaction appears relative to total reports for tyloxapol.

1
Diarrhoea35.3%6
2
Thrombocytopenia29.4%5
3
Liver Function Test Increased29.4%5
4
Polyneuropathy29.4%5
5
Drug Hypersensitivity17.6%3
6
Pancreatic Carcinoma17.6%3
7
Urticaria17.6%3
8
Migraine5.9%1
9
Osteonecrosis Of Jaw5.9%1
10
Malignant Neoplasm Progression5.9%1
11
Neoplasm Progression5.9%1
12
Viral Upper Respiratory Tract Infection5.9%1
13
Urosepsis5.9%1
14
Acute Kidney Injury5.9%1
15
Catheter Site Infection5.9%1

These are voluntary reports and do not establish that tyloxapol caused these reactions.

Report severity

58.8%Serious10 reports
11.8%Hospitalizations2 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tyloxapol drug interactions

Other drugs that appear in adverse event reports alongside tyloxapol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Paclitaxel29.4%5
2
Gemcitabine23.5%4
3
Tramadol-hydrochloride17.6%3
4
Gabapentin11.8%2
5
Acetaminophen11.8%2
6
Oxycodone11.8%2
7
Ciprofloxacin11.8%2
8
Cetyl-alcohol5.9%1
9
Colfosceril-palmitate5.9%1
10
Denosumab5.9%1
11
Mycophenolate5.9%1
12
Celecoxib5.9%1
13
Erythromycin5.9%1
14
Carbamazepine5.9%1
15
Aspirin5.9%1

Taken alongside

1
Ondansetron41.2%7
2
Cetyl-alcohol35.3%6
3
Colfosceril-palmitate35.3%6
4
Alprazolam29.4%5
5
Enoxaparin-sodium29.4%5
6
Prednisone11.8%2
7
Acetaminophen11.8%2
8
Oxycodone11.8%2
9
Epinastine-hydrochloride5.9%1
10
Celecoxib5.9%1
11
Diclofenac5.9%1
12
Amitriptyline-hydrochloride5.9%1
13
Betamethasone5.9%1
14
Lidocaine5.9%1
15
Sitagliptin5.9%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tyloxapol side effects

76.5% of tyloxapol adverse event reports involve female patients and 0.0% involve male patients. The largest age group is adult at 75%. These figures reflect who reports side effects, not underlying risk.

Sex

Female76.5%
Male0.0%
Unknown23.5%

Age group

< 28.3%
2–110.0%
12–178.3%
18–6475.0%
65+8.3%

What is tyloxapol used for

Conditions and purposes for which patients were taking tyloxapol when the adverse event was reported.

Product Used For Unknown IndicationPruritusProduct Used For Unknown IndicationSinusitis

Tyloxapol brand names and reporting trend

Tyloxapol is sold under the brand name Exosurf Neonatal.

Brand names

Exosurf Neonatal10

Quarterly reports (20042024)

20042024

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tyloxapol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.