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Tropicamide Side Effects

The most commonly reported side effects of tropicamide include vision blurred, off label use, and eye pain, based on 1,808 FDA adverse event reports from 2004 to 2025. 5.6% of reports found the drug to be ineffective.

Tropicamide side effects

Percentages show how often each reaction appears relative to total reports for tropicamide.

1
Vision Blurred9.1%164
2
Off Label Use9.1%164
3
Eye Pain5.8%104
4
Drug Ineffective5.6%101
5
Headache5.3%96
6
Visual Acuity Reduced4.9%88
7
Visual Impairment4.8%87
8
Dizziness3.8%69
9
Cataract3.8%68
10
Eye Irritation3.7%66
11
Nausea3.6%65
12
Vitreous Floaters3.6%65
13
Toxic Anterior Segment Syndrome3.5%64
14
Fatigue3.5%63
15
Eye Inflammation3.4%61

These are voluntary reports and do not establish that tropicamide caused these reactions.

Report severity

82.5%Serious1,491 reports
25.1%Hospitalizations453 reports
4.3%Fatal77 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tropicamide drug interactions

Other drugs that appear in adverse event reports alongside tropicamide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Phenylephrine11.3%204
2
Ranibizumab9.5%171
3
Bevacizumab9.2%167
4
Dexamethasone6.3%113
5
Sodium-chloride6.0%109
6
Potassium-chloride5.8%104
7
Calcium-chloride5.0%90
8
Magnesium-chloride4.9%89
9
Sodium-acetate4.8%86
10
Sodium-citrate4.8%86
11
Lidocaine4.7%85
12
Prednisone4.2%76
13
Povidone-iodine4.2%76
14
Proparacaine-hydrochloride4.1%75
15
Moxifloxacin-hydrochloride4.0%73

Taken alongside

1
Phenylephrine19.0%344
2
Aspirin10.9%197
3
Lidocaine9.7%175
4
Povidone-iodine9.0%162
5
Proparacaine-hydrochloride8.7%158
6
Acetaminophen8.5%153
7
Dexamethasone7.6%138
8
Atorvastatin-calcium7.4%133
9
Moxifloxacin-hydrochloride6.6%119
10
Levothyroxine-sodium6.1%111
11
Metformin5.9%106
12
Amlodipine5.4%97
13
Pantoprazole-sodium4.8%87
14
Timolol4.6%84
15
Prednisolone4.5%82

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tropicamide side effects

47.8% of tropicamide adverse event reports involve female patients and 36.0% involve male patients. The largest age group is adult at 45%. These figures reflect who reports side effects, not underlying risk.

Sex

Female47.8%
Male36.0%
Unknown16.2%

Age group

< 26.7%
2–113.9%
12–173.0%
18–6445.3%
65+41.0%

What is tropicamide used for

Conditions and purposes for which patients were taking tropicamide when the adverse event was reported.

Age-related Macular DegenerationAnaesthesiaAngiogram RetinaAntibiotic TherapyAstigmatismAccommodation DisorderAdverse Drug ReactionAnaesthesia EyeAngle Closure GlaucomaBehcet's SyndromeBacterial EndophthalmitisCataractCataract OperationChorioretinal DisorderChorioretinitis

Showing 15 of 148 indications

Tropicamide brand names and reporting trend

Tropicamide is sold under the brand name Mydriacyl.

Brand names

Mydriacyl1,583

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tropicamide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.