OpenClaim

Triple Side Effects

The most commonly reported side effects of triple include drug hypersensitivity, nausea, and nausea, based on 33 FDA adverse event reports from 2004 to 2024. 6.1% of reports found the drug to be ineffective.

Triple side effects

Percentages show how often each reaction appears relative to total reports for triple.

1
Drug Hypersensitivity45.5%15
2
Nausea9.1%3
3
Nausea6.1%2
4
Pyrexia6.1%2
5
Decreased Appetite6.1%2
6
Fatigue6.1%2
7
Product Use Issue6.1%2
8
Drug Dose Omission6.1%2
9
Drug Ineffective6.1%2
10
Urticaria6.1%2
11
Hepatic Enzyme Increased6.1%2
12
Anaesthetic Complication3.0%1
13
Dizziness3.0%1
14
Feeling Abnormal3.0%1
15
Feeling Hot3.0%1

These are voluntary reports and do not establish that triple caused these reactions.

Report severity

42.4%Serious14 reports
18.2%Hospitalizations6 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Triple drug interactions

Other drugs that appear in adverse event reports alongside triple. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Etanercept18.2%6
2
Acetaminophen12.1%4
3
Sulfathiazole9.1%3
4
Cephalexin9.1%3
5
Adalimumab9.1%3
6
Morphine-sulfate9.1%3
7
Sulfacetamide6.1%2
8
Sertraline-hydrochloride6.1%2
9
Ethinyl-estradiol6.1%2
10
Tetracycline6.1%2
11
Cyclizine-lactate6.1%2
12
Metolazone6.1%2
13
Penicillin6.1%2
14
Nalidixic-acid6.1%2
15
Calcitonin6.1%2

Taken alongside

1
Prednisone12.1%4
2
Ergocalciferol12.1%4
3
Oxycodone12.1%4
4
Carvedilol9.1%3
5
Metformin9.1%3
6
Diazepam9.1%3
7
Albuterol9.1%3
8
Tizanidine-hydrochloride9.1%3
9
Semaglutide9.1%3
10
Sulfacetamide6.1%2
11
Sulfathiazole6.1%2
12
Omeprazole6.1%2
13
Lactulose6.1%2
14
Penicillin6.1%2
15
Levothyroxine-sodium6.1%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports triple side effects

87.9% of triple adverse event reports involve female patients and 3.0% involve male patients. The largest age group is adult at 62%. These figures reflect who reports side effects, not underlying risk.

Sex

Female87.9%
Male3.0%
Unknown9.1%

Age group

< 20.0%
2–113.8%
12–170.0%
18–6461.5%
65+34.6%

What is triple used for

Conditions and purposes for which patients were taking triple when the adverse event was reported.

Antibacterial ProphylaxisHelicobacter GastritisProduct Used For Unknown IndicationProphylaxisProduct Used For Unknown IndicationPsoriatic ArthropathyVitamin Supplementation

Triple brand names and reporting trend

Triple is sold under the brand name Triple Sulfa.

Brand names

Triple Sulfa30

Quarterly reports (20042024)

20042024

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking triple with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.