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Trimethaphan Side Effects

The most commonly reported side effects of trimethaphan include injection site swelling, injection site pruritus, and upper respiratory tract infection, based on 4 FDA adverse event reports from 2010 to 2019.

Trimethaphan side effects

Percentages show how often each reaction appears relative to total reports for trimethaphan.

1
Injection Site Swelling25.0%1
2
Injection Site Pruritus25.0%1
3
Upper Respiratory Tract Infection25.0%1
4
Peripheral Swelling25.0%1
5
Balance Disorder25.0%1
6
Therapeutic Response Shortened25.0%1
7
Fall25.0%1
8
Blood Pressure Decreased25.0%1
9
Extrapyramidal Disorder25.0%1
10
Dyskinesia25.0%1

These are voluntary reports and do not establish that trimethaphan caused these reactions.

Report severity

0.0%Serious0 reports
0.0%Hospitalizations0 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Trimethaphan drug interactions

Other drugs that appear in adverse event reports alongside trimethaphan. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab25.0%1
2
Omeprazole25.0%1
3
Isradipine25.0%1
4
Modafinil25.0%1
5
Carbidopa25.0%1
6
Levodopa25.0%1
7
Lisinopril25.0%1

Taken alongside

1
Ranitidine25.0%1
2
Valacyclovir-hydrochloride25.0%1
3
Ciprofloxacin25.0%1
4
Loratadine25.0%1
5
Hydroxychloroquine-sulfate25.0%1
6
Etodolac25.0%1
7
Furosemide25.0%1
8
Acetaminophen25.0%1
9
Ergocalciferol25.0%1
10
Folic-acid25.0%1
11
Metoprolol25.0%1
12
Omeprazole25.0%1
13
Spironolactone25.0%1
14
Tramadol-hydrochloride25.0%1
15
Clonazepam25.0%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports trimethaphan side effects

75.0% of trimethaphan adverse event reports involve female patients and 25.0% involve male patients. The largest age group is adult at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female75.0%
Male25.0%
Unknown0.0%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6466.7%
65+33.3%

What is trimethaphan used for

Conditions and purposes for which patients were taking trimethaphan when the adverse event was reported.

ContraceptionProphylaxis Of Nausea And Vomiting

Trimethaphan brand names and reporting trend

Trimethaphan is sold under the brand name Arfonad.

Brand names

Arfonad4

Quarterly reports (20102019)

201020162019

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking trimethaphan with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.