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Triheptanoin Side Effects

The most commonly reported side effects of triheptanoin include vomiting, diarrhoea, and rhabdomyolysis, based on 515 FDA adverse event reports from 2020 to 2025.

Triheptanoin side effects

Percentages show how often each reaction appears relative to total reports for triheptanoin.

1
Vomiting15.9%82
2
Diarrhoea13.8%71
3
Rhabdomyolysis10.3%53
4
Off Label Use9.5%49
5
Abdominal Pain Upper7.8%40
6
Blood Creatine Phosphokinase Increased6.8%35
7
Abdominal Discomfort6.6%34
8
Death5.8%30
9
Nausea5.2%27
10
Hospitalisation4.7%24
11
Gastrointestinal Disorder4.5%23
12
Illness4.3%22
13
Abdominal Pain3.9%20
14
Metabolic Disorder3.5%18
15
Product Dose Omission Issue3.1%16

These are voluntary reports and do not establish that triheptanoin caused these reactions.

Report severity

63.5%Serious327 reports
48.7%Hospitalizations251 reports
12.0%Fatal62 reports

Seriousness is determined by the reporter, not by OpenClaim.

Triheptanoin drug interactions

Other drugs that appear in adverse event reports alongside triheptanoin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Valproic-acid1.0%5
2
Lacosamide1.0%5
3
Zonisamide1.0%5
4
Levetiracetam1.0%5
5
Carbamazepine1.0%5
6
Furosemide0.6%3
7
Propranolol-hydrochloride0.4%2
8
Hydroxyurea0.4%2
9
Peginterferon0.4%2
10
Ruxolitinib0.4%2
11
Palivizumab0.2%1
12
Hydrochlorothiazide0.2%1
13
Diazoxide0.2%1
14
Acetazolamide0.2%1
15
Amiloride-hydrochloride0.2%1

Taken alongside

1
Levocarnitine15.0%77
2
Ergocalciferol4.5%23
3
Omeprazole3.5%18
4
Famotidine2.7%14
5
Cetirizine-hydrochloride2.7%14
6
Fluticasone2.1%11
7
Ibuprofen2.1%11
8
Ferrous-sulfate2.1%11
9
Polyethylene-glycol-33501.9%10
10
Furosemide1.7%9
11
Enalapril-maleate1.7%9
12
Bupropion1.7%9
13
Levothyroxine-sodium1.6%8
14
Ascorbic-acid1.6%8
15
Spironolactone1.4%7

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports triheptanoin side effects

44.5% of triheptanoin adverse event reports involve female patients and 47.2% involve male patients. The largest age group is child at 40%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.5%
Male47.2%
Unknown8.3%

Age group

< 227.1%
2–1139.6%
12–1714.7%
18–6417.6%
65+1.1%

What is triheptanoin used for

Conditions and purposes for which patients were taking triheptanoin when the adverse event was reported.

Adult Polyglucosan Body DiseaseAmino Acid Metabolism DisorderBlood Pyruvic Acid AbnormalCarnitine Palmitoyltransferase DeficiencyCarnitine-acylcarnitine Translocase DeficiencyCardiomyopathyCarnitine Palmitoyltransferase DeficiencyCarnitine-acylcarnitine Translocase DeficiencyEpilepsyEpilepsyFatty Acid Oxidation DisorderFatty Acid Oxidation DisorderGene MutationGlycogen Storage Disease Type IGene Mutation

Showing 15 of 42 indications

Triheptanoin brand names and reporting trend

Triheptanoin is sold under the brand name Dojolvi.

Brand names

Dojolvi56

Quarterly reports (20202025)

2020202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking triheptanoin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.