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Tridihexethyl Side Effects

The most commonly reported side effects of tridihexethyl include acute kidney injury, chronic kidney disease, and toxicity to various agents, based on 89 FDA adverse event reports from 2004 to 2025.

Tridihexethyl side effects

Percentages show how often each reaction appears relative to total reports for tridihexethyl.

1
Acute Kidney Injury6.7%6
2
Chronic Kidney Disease6.7%6
3
Toxicity To Various Agents6.7%6
4
Vomiting5.6%5
5
Fatigue5.6%5
6
Nausea4.5%4
7
Dyspnoea4.5%4
8
Diarrhoea4.5%4
9
Fall4.5%4
10
Injection Site Pain4.5%4
11
Drug Hypersensitivity4.5%4
12
Arthralgia4.5%4
13
Renal Failure4.5%4
14
Foetal Exposure During Pregnancy4.5%4
15
Premature Baby4.5%4

These are voluntary reports and do not establish that tridihexethyl caused these reactions.

Report severity

69.7%Serious62 reports
20.2%Hospitalizations18 reports
13.5%Fatal12 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tridihexethyl drug interactions

Other drugs that appear in adverse event reports alongside tridihexethyl. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Fentanyl11.2%10
2
Bupivacaine10.1%9
3
Sodium-oxybate6.7%6
4
Bisoprolol-fumarate5.6%5
5
Enoxaparin-sodium5.6%5
6
Methyldopa5.6%5
7
Aspirin5.6%5
8
Metformin5.6%5
9
Gemfibrozil5.6%5
10
Omeprazole4.5%4
11
Esomeprazole4.5%4
12
Citalopram-hydrobromide4.5%4
13
Sodium-chloride3.4%3
14
Amphetamine3.4%3
15
Pregabalin2.2%2

Taken alongside

1
Acetaminophen33.7%30
2
Ergocalciferol20.2%18
3
Albuterol16.9%15
4
Gabapentin15.7%14
5
Hydrocodone13.5%12
6
Aspirin13.5%12
7
Fluticasone13.5%12
8
Lidocaine13.5%12
9
Diazepam12.4%11
10
Alprazolam12.4%11
11
Diphenhydramine12.4%11
12
Ibuprofen12.4%11
13
Prednisone11.2%10
14
Ondansetron11.2%10
15
Pantoprazole-sodium11.2%10

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tridihexethyl side effects

49.4% of tridihexethyl adverse event reports involve female patients and 36.0% involve male patients. The largest age group is adult at 59%. These figures reflect who reports side effects, not underlying risk.

Sex

Female49.4%
Male36.0%
Unknown14.6%

Age group

< 21.8%
2–113.6%
12–178.9%
18–6458.9%
65+26.8%

What is tridihexethyl used for

Conditions and purposes for which patients were taking tridihexethyl when the adverse event was reported.

AnaesthesiaAnaesthesiaAnaesthetic PremedicationDebridementDrug Exposure During PregnancyDrug AbuseFoetal Exposure During PregnancyHaemodialysisHypoaesthesiaHigh Risk Sexual BehaviourInduction Of AnaesthesiaLocal AnaesthesiaMuscle DisorderOsteoarthritisPain

Showing 15 of 21 indications

Tridihexethyl brand names and reporting trend

Tridihexethyl is sold under the brand name Pathilon.

Brand names

Pathilon89

Quarterly reports (20042025)

2005201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tridihexethyl with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.