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Triclosan Side Effects

The most commonly reported side effects of triclosan include vomiting, type 2 diabetes mellitus, and weight increased, based on 1,277 FDA adverse event reports from 2004 to 2025.

Triclosan side effects

Percentages show how often each reaction appears relative to total reports for triclosan.

1
Vomiting15.7%201
2
Type 2 Diabetes Mellitus15.5%198
3
Weight Increased15.0%192
4
Urticaria14.5%185
5
Hypertension14.0%179
6
Hypersensitivity13.9%178
7
Hypoaesthesia13.7%175
8
Osteoarthritis13.5%173
9
Wound Infection13.2%169
10
Nasopharyngitis13.2%168
11
Wound12.9%165
12
Irritable Bowel Syndrome12.9%165
13
Infusion Related Reaction12.9%165
14
Nausea12.8%164
15
Wheezing12.8%163

These are voluntary reports and do not establish that triclosan caused these reactions.

Report severity

51.7%Serious660 reports
12.2%Hospitalizations156 reports
29.4%Fatal376 reports

Seriousness is determined by the reporter, not by OpenClaim.

Triclosan drug interactions

Other drugs that appear in adverse event reports alongside triclosan. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-fluoride78.3%1,000
2
Abatacept29.4%375
3
Hydrocortisone26.6%340
4
Methotrexate25.8%329
5
Diclofenac25.7%328
6
Oxycodone25.5%325
7
Sulfasalazine25.5%325
8
Tramadol-hydrochloride25.4%324
9
Tocilizumab25.4%324
10
Tofacitinib25.4%324
11
Triamcinolone25.3%323
12
Ustekinumab25.3%323
13
Mesalamine25.3%323
14
Naproxen25.3%323
15
Pseudoephedrine25.2%322

Taken alongside

1
Pantoprazole-sodium8.9%114
2
Acetaminophen7.2%92
3
Quetiapine-fumarate6.0%76
4
Ergocalciferol5.6%71
5
Cetirizine-hydrochloride5.5%70
6
Sulfasalazine5.5%70
7
Lisinopril5.4%69
8
Naproxen5.3%68
9
Lorazepam5.1%65
10
Diclofenac5.0%64
11
Tofacitinib5.0%64
12
Methylprednisolone4.9%62
13
Dihydrocodeine-bitartrate4.9%62
14
Calcium4.8%61
15
Pregabalin4.8%61

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports triclosan side effects

67.5% of triclosan adverse event reports involve female patients and 22.9% involve male patients. The largest age group is adult at 66%. These figures reflect who reports side effects, not underlying risk.

Sex

Female67.5%
Male22.9%
Unknown9.6%

Age group

< 21.2%
2–112.4%
12–172.1%
18–6465.7%
65+28.6%

What is triclosan used for

Conditions and purposes for which patients were taking triclosan when the adverse event was reported.

AcneAntibiotic ProphylaxisAntiviral ProphylaxisAnxietyBreath OdourBenign Familial PemphigusCentral Nervous System LupusDental CareDental CariesDental CleaningDental Disorder ProphylaxisDental PlaqueDental TreatmentDermatitis AcneiformDermatitis Atopic

Showing 15 of 46 indications

Triclosan brand names and reporting trend

Triclosan is sold under the brand name Colgate Total.

Brand names

Colgate Total778

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking triclosan with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.