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Toripalimab Side Effects

The most commonly reported side effects of toripalimab include myelosuppression, off label use, and white blood cell count decreased, based on 1,581 FDA adverse event reports from 2019 to 2025.

Toripalimab side effects

Percentages show how often each reaction appears relative to total reports for toripalimab.

1
Myelosuppression42.1%665
2
Off Label Use18.4%291
3
White Blood Cell Count Decreased9.7%153
4
Neutrophil Count Decreased4.7%75
5
Hypothyroidism4.6%72
6
Rash4.6%72
7
Anaemia4.4%70
8
Nausea4.2%67
9
Vomiting4.1%65
10
Platelet Count Decreased3.8%60
11
Diarrhoea3.7%58
12
Pyrexia3.6%57
13
Neutropenia3.5%55
14
Thrombocytopenia3.2%50
15
Fatigue3.0%47

These are voluntary reports and do not establish that toripalimab caused these reactions.

Report severity

99.6%Serious1,574 reports
59.2%Hospitalizations936 reports
5.5%Fatal87 reports

Seriousness is determined by the reporter, not by OpenClaim.

Toripalimab drug interactions

Other drugs that appear in adverse event reports alongside toripalimab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Cisplatin21.0%332
2
Paclitaxel20.8%329
3
Gemcitabine15.5%245
4
Carboplatin12.8%203
5
Lenvatinib-mesylate10.3%163
6
Oxaliplatin5.1%81
7
Etoposide5.0%79
8
Docetaxel4.7%75
9
Pembrolizumab3.7%59
10
Bevacizumab3.7%58
11
Tislelizumab-jsgr3.5%56
12
Fluorouracil3.3%52
13
Capecitabine3.1%49
14
Atezolizumab3.1%49
15
Cetuximab2.7%42

Taken alongside

1
Sodium-chloride21.5%340
2
Entecavir5.1%81
3
Dextrose4.2%67
4
Paclitaxel2.7%43
5
Cisplatin2.2%34
6
Carboplatin1.6%25
7
Nifedipine1.4%22
8
Amlodipine1.3%21
9
Levothyroxine-sodium1.2%19
10
Gemcitabine0.9%15
11
Oxaliplatin0.8%13
12
Tenofovir0.8%12
13
Pemetrexed0.7%11
14
Lenvatinib-mesylate0.7%11
15
Estropipate0.7%11

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports toripalimab side effects

7.3% of toripalimab adverse event reports involve female patients and 16.4% involve male patients. The largest age group is adult at 65%. These figures reflect who reports side effects, not underlying risk.

Sex

Female7.3%
Male16.4%
Unknown76.3%

Age group

< 20.0%
2–110.2%
12–170.5%
18–6465.4%
65+33.8%

What is toripalimab used for

Conditions and purposes for which patients were taking toripalimab when the adverse event was reported.

Adenocarcinoma GastricAggressionAcinar Cell Carcinoma Of PancreasAcute Kidney InjuryAdenocarcinomaAdenocarcinoma GastricAdenocarcinoma Of ColonAdenocarcinoma Of The CervixAdenocarcinoma PancreasAdenosquamous Cell Lung Cancer Stage IiiAlveolar Soft Part SarcomaAngiocentric LymphomaBile Duct AdenocarcinomaBile Duct CancerBile Duct Cancer Recurrent

Showing 15 of 263 indications

Toripalimab brand names and reporting trend

Toripalimab is sold under the brand name Loqtorzi.

Brand names

Loqtorzi2,077

Quarterly reports (20192025)

2019202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking toripalimab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.