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Toremifene Side Effects

The most commonly reported side effects of toremifene include general physical health deterioration, dyspnoea, and acute kidney injury, based on 3,782 FDA adverse event reports from 2004 to 2025.

Toremifene side effects

Percentages show how often each reaction appears relative to total reports for toremifene.

1
General Physical Health Deterioration6.1%232
2
Dyspnoea5.8%218
3
Acute Kidney Injury4.9%186
4
Drug Interaction4.6%173
5
Cardiac Failure4.4%167
6
Nausea4.0%150
7
Pneumonia3.7%140
8
Fall3.7%139
9
Anaemia3.6%138
10
Fatigue3.4%128
11
Diarrhoea3.1%117
12
Oedema Peripheral2.8%105
13
Gastrointestinal Haemorrhage2.6%100
14
Dizziness2.6%98
15
Asthenia2.5%96

These are voluntary reports and do not establish that toremifene caused these reactions.

Report severity

97.6%Serious3,693 reports
68.7%Hospitalizations2,597 reports
17.9%Fatal677 reports

Seriousness is determined by the reporter, not by OpenClaim.

Toremifene drug interactions

Other drugs that appear in adverse event reports alongside toremifene. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Aspirin5.8%220
2
Rivaroxaban5.5%208
3
Spironolactone3.4%128
4
Paclitaxel3.3%124
5
Valsartan3.0%112
6
Metformin2.5%96
7
Amiodarone-hydrochloride2.4%89
8
Adalimumab2.3%87
9
Bevacizumab2.2%83
10
Allopurinol2.1%81
11
Simvastatin2.1%79
12
Esomeprazole2.0%77
13
Zoledronic-acid2.0%74
14
Quetiapine-fumarate2.0%74
15
Carboplatin1.9%73

Taken alongside

1
Aspirin17.5%663
2
Spironolactone11.9%450
3
Allopurinol11.2%423
4
Ramipril10.8%407
5
Pantoprazole-sodium10.7%405
6
Simvastatin10.1%382
7
Bisoprolol-fumarate10.0%380
8
Metoprolol8.7%329
9
Amlodipine7.9%300
10
Insulin7.8%295
11
Esomeprazole6.2%234
12
Metformin5.6%212
13
Atorvastatin-calcium5.4%203
14
Pregabalin5.2%198
15
Levothyroxine-sodium5.1%194

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports toremifene side effects

49.4% of toremifene adverse event reports involve female patients and 44.3% involve male patients. The largest age group is elderly at 72%. These figures reflect who reports side effects, not underlying risk.

Sex

Female49.4%
Male44.3%
Unknown6.3%

Age group

< 20.0%
2–11<0.1%
12–17<0.1%
18–6427.6%
65+72.2%

What is toremifene used for

Conditions and purposes for which patients were taking toremifene when the adverse event was reported.

Acute Hepatic FailureAcute Myocardial InfarctionAdverse EventAntioestrogen TherapyAnuriaAscitesAtrial FibrillationAtrial FlutterAdenoid Cystic Carcinoma Of Salivary GlandBlood Pressure AbnormalBone DisorderBreast CancerBreast Cancer FemaleBreast Cancer MaleBreast Cancer Metastatic

Showing 15 of 149 indications

Toremifene brand names and reporting trend

Toremifene is sold under the brand name Fareston.

Brand names

Fareston3,717

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking toremifene with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.