The most commonly reported side effects of tolcapone include hallucination, fall, and death, based on 375 FDA adverse event reports from 2004 to 2025. 2.4% of reports found the drug to be ineffective.
Percentages show how often each reaction appears relative to total reports for tolcapone.
These are voluntary reports and do not establish that tolcapone caused these reactions.
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Other drugs that appear in adverse event reports alongside tolcapone. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
28.8% of tolcapone adverse event reports involve female patients and 65.9% involve male patients. The largest age group is elderly at 69%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking tolcapone when the adverse event was reported.
Tolcapone is sold under the brand name Tasmar.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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