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Tolazamide Side Effects

The most commonly reported side effects of tolazamide include dyspnoea, blood glucose increased, and vomiting, based on 82 FDA adverse event reports from 2004 to 2025.

Tolazamide side effects

Percentages show how often each reaction appears relative to total reports for tolazamide.

1
Dyspnoea7.3%6
2
Blood Glucose Increased7.3%6
3
Vomiting6.1%5
4
Fatigue6.1%5
5
Myocardial Infarction6.1%5
6
Nausea4.9%4
7
Renal Failure4.9%4
8
Decreased Appetite4.9%4
9
Dizziness4.9%4
10
Bladder Cancer4.9%4
11
Hypotension3.7%3
12
Arthralgia3.7%3
13
Chest Pain3.7%3
14
Asthenia3.7%3
15
Back Pain3.7%3

These are voluntary reports and do not establish that tolazamide caused these reactions.

Report severity

72.0%Serious59 reports
40.2%Hospitalizations33 reports
11.0%Fatal9 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tolazamide drug interactions

Other drugs that appear in adverse event reports alongside tolazamide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Pioglitazone-hydrochloride11.0%9
2
Metformin6.1%5
3
Exenatide-synthetic6.1%5
4
Lenalidomide6.1%5
5
Atorvastatin-calcium4.9%4
6
Glyburide3.7%3
7
Olanzapine3.7%3
8
Glipizide3.7%3
9
Alteplase3.7%3
10
Simvastatin2.4%2
11
Insulin2.4%2
12
Rofecoxib2.4%2
13
Diltiazem2.4%2
14
Acetazolamide2.4%2
15
Sunitinib-malate2.4%2

Taken alongside

1
Metformin25.6%21
2
Lisinopril24.4%20
3
Aspirin20.7%17
4
Hydrochlorothiazide15.9%13
5
Simvastatin14.6%12
6
Furosemide14.6%12
7
Insulin14.6%12
8
Metoprolol13.4%11
9
Omeprazole13.4%11
10
Albuterol11.0%9
11
Potassium-chloride11.0%9
12
Atenolol11.0%9
13
Amlodipine11.0%9
14
Lovastatin9.8%8
15
Warfarin9.8%8

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tolazamide side effects

39.0% of tolazamide adverse event reports involve female patients and 48.8% involve male patients. The largest age group is elderly at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female39.0%
Male48.8%
Unknown12.2%

Age group

< 20.0%
2–111.8%
12–170.0%
18–6447.4%
65+50.9%

What is tolazamide used for

Conditions and purposes for which patients were taking tolazamide when the adverse event was reported.

Accidental Exposure To Product By ChildAccidental PoisoningCrohn's DiseaseDiabetes MellitusDiuretic TherapyDrug Use For Unknown IndicationProduct Used For Unknown IndicationProduct Used For Unknown Indication

Tolazamide brand names and reporting trend

Tolazamide is sold under the brand name Tolazamide.

Brand names

Tolazamide65

Quarterly reports (20042025)

2004200520152025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tolazamide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.