OpenClaim

Titanium Side Effects

The most commonly reported side effects of titanium include off label use, nausea, and vomiting, based on 228 FDA adverse event reports from 2004 to 2025.

Titanium side effects

Percentages show how often each reaction appears relative to total reports for titanium.

1
Off Label Use21.5%49
2
Nausea19.7%45
3
Vomiting19.7%45
4
Dyspnoea19.3%44
5
Abdominal Distension19.3%44
6
Abdominal Pain18.9%43
7
Condition Aggravated18.4%42
8
Dry Mouth18.4%42
9
Diabetes Mellitus18.0%41
10
General Physical Health Deterioration18.0%41
11
Ascites18.0%41
12
Somnolence18.0%41
13
Appendicolith17.5%40
14
Appendicitis17.5%40
15
Drug Hypersensitivity17.1%39

These are voluntary reports and do not establish that titanium caused these reactions.

Report severity

90.4%Serious206 reports
60.1%Hospitalizations137 reports
36.8%Fatal84 reports

Seriousness is determined by the reporter, not by OpenClaim.

Titanium drug interactions

Other drugs that appear in adverse event reports alongside titanium. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Acetaminophen34.6%79
2
Ondansetron31.6%72
3
Gabapentin30.7%70
4
Betamethasone30.3%69
5
Simvastatin29.8%68
6
Dexlansoprazole29.8%68
7
Ipratropium-bromide29.4%67
8
Metronidazole28.9%66
9
Dextrose28.9%66
10
Sodium-citrate28.9%66
11
Insulin28.9%66
12
Albuterol28.9%66
13
Amiodarone-hydrochloride28.9%66
14
Lansoprazole28.9%66
15
Allopurinol28.9%66

Taken alongside

1
Estropipate21.1%48
2
Amlodipine19.7%45
3
Ergocalciferol19.7%45
4
Cholecalciferol15.8%36
5
Riboflavin14.5%33
6
Acetaminophen12.7%29
7
Ascorbic-acid10.5%24
8
Beta-carotene10.1%23
9
Pantoprazole-sodium9.2%21
10
Acyclovir8.3%19
11
Ondansetron7.9%18
12
Amoxicillin7.9%18
13
Albuterol7.5%17
14
Omeprazole7.0%16
15
Darbepoetin-alfa6.6%15

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports titanium side effects

41.2% of titanium adverse event reports involve female patients and 48.2% involve male patients. The largest age group is elderly at 65%. These figures reflect who reports side effects, not underlying risk.

Sex

Female41.2%
Male48.2%
Unknown10.5%

Age group

< 21.1%
2–111.1%
12–171.1%
18–6431.9%
65+64.9%

What is titanium used for

Conditions and purposes for which patients were taking titanium when the adverse event was reported.

ArthritisChronic Obstructive Pulmonary DiseaseColitisComputerised TomogramChronic Obstructive Pulmonary DiseaseConstipationDermatitis DiaperDyspnoeaFunctional Gastrointestinal DisorderHaemorrhoidsHer-2 Positive Gastric CancerHaemorrhoidsHistoplasmosisIll-defined DisorderMultiple Sclerosis

Showing 15 of 21 indications

Titanium brand names and reporting trend

Titanium is sold under the brand name Anthelios 40.

Brand names

Anthelios 40237

Quarterly reports (20042025)

200420202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking titanium with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.