OpenClaim

Tislelizumab Side Effects

The most commonly reported side effects of tislelizumab include myelosuppression, white blood cell count decreased, and neutrophil count decreased, based on 6,072 FDA adverse event reports from 2010 to 2025.

Tislelizumab side effects

Percentages show how often each reaction appears relative to total reports for tislelizumab.

1
Myelosuppression43.4%2,635
2
White Blood Cell Count Decreased6.2%376
3
Neutrophil Count Decreased4.9%300
4
Hepatic Function Abnormal4.4%267
5
Pruritus4.0%244
6
Rash4.0%240
7
Platelet Count Decreased3.6%221
8
Pyrexia3.5%212
9
Nausea3.4%209
10
Off Label Use3.2%196
11
Liver Injury3.0%182
12
Diarrhoea2.8%173
13
Decreased Appetite2.7%163
14
Asthenia2.5%151
15
Anaemia2.5%149

These are voluntary reports and do not establish that tislelizumab caused these reactions.

Report severity

99.8%Serious6,062 reports
50.7%Hospitalizations3,078 reports
2.3%Fatal138 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tislelizumab drug interactions

Other drugs that appear in adverse event reports alongside tislelizumab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Paclitaxel20.0%1,212
2
Carboplatin15.5%939
3
Cisplatin13.8%837
4
Oxaliplatin7.9%482
5
Gemcitabine7.6%461
6
Pemetrexed5.8%354
7
Capecitabine4.9%296
8
Docetaxel4.6%278
9
Bevacizumab4.5%274
10
Etoposide3.9%239
11
Fluorouracil3.7%227
12
Lenvatinib-mesylate2.6%160
13
Irinotecan-hydrochloride2.0%121
14
Islelizumab-jsgr1.5%93
15
Zanidatamab-hrii1.4%82

Taken alongside

1
Sodium-chloride22.9%1,392
2
Dextrose6.2%375
3
Paclitaxel4.5%271
4
Carboplatin3.0%183
5
Dexamethasone1.6%99
6
Cisplatin1.4%84
7
Omeprazole1.3%76
8
Oxaliplatin1.1%65
9
Capecitabine1.1%64
10
Gemcitabine1.0%61
11
Acetaminophen1.0%60
12
Ondansetron1.0%60
13
Bevacizumab1.0%59
14
Lenvatinib-mesylate1.0%58
15
Etoposide0.8%51

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tislelizumab side effects

5.5% of tislelizumab adverse event reports involve female patients and 15.8% involve male patients. The largest age group is adult at 53%. These figures reflect who reports side effects, not underlying risk.

Sex

Female5.5%
Male15.8%
Unknown78.7%

Age group

< 20.0%
2–110.0%
12–170.2%
18–6452.6%
65+47.2%

What is tislelizumab used for

Conditions and purposes for which patients were taking tislelizumab when the adverse event was reported.

Acute Myeloid LeukaemiaAdenocarcinomaAdenocarcinoma GastricAbdominal NeoplasmAcute Myeloid LeukaemiaAdenocarcinomaAdenocarcinoma GastricAdenocarcinoma Gastric Stage IiiAdenocarcinoma Gastric Stage IvAdenocarcinoma MetastaticAdenocarcinoma Of AppendixAdenocarcinoma Of ColonAdenocarcinoma Of The CervixAdenosquamous Carcinoma Of The CervixAdenosquamous Cell Carcinoma

Showing 15 of 407 indications

Tislelizumab brand names and reporting trend

Tislelizumab is sold under the brand name Tevimbra.

Brand names

Tevimbra15,325

Quarterly reports (20102025)

201020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tislelizumab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.