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Tirofiban Side Effects

The most commonly reported side effects of tirofiban include haemorrhage, angina pectoris, and haemorrhage intracranial, based on 2,937 FDA adverse event reports from 2004 to 2025. 1.4% of reports found the drug to be ineffective.

Tirofiban side effects

Percentages show how often each reaction appears relative to total reports for tirofiban.

1
Haemorrhage11.8%346
2
Angina Pectoris6.3%185
3
Haemorrhage Intracranial6.0%177
4
Myocardial Infarction5.5%163
5
Thrombocytopenia5.4%160
6
Thrombocytopenia5.2%152
7
Cardiac Failure Acute4.0%117
8
Death3.9%114
9
Acute Respiratory Failure3.4%100
10
Cerebral Haemorrhage3.2%94
11
Vascular Stent Thrombosis2.8%81
12
Cardiac Failure2.4%71
13
Myocardial Infarction2.0%58
14
Infarction1.8%53
15
Drug Ineffective1.4%41

These are voluntary reports and do not establish that tirofiban caused these reactions.

Report severity

88.9%Serious2,611 reports
16.2%Hospitalizations477 reports
16.4%Fatal483 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tirofiban drug interactions

Other drugs that appear in adverse event reports alongside tirofiban. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Aspirin10.5%307
2
Heparin6.9%202
3
Ticagrelor5.9%172
4
Gemfibrozil4.5%132
5
Clopidogrel-bisulfate3.5%102
6
Enoxaparin-sodium2.0%60
7
Alteplase1.2%35
8
Fondaparinux-sodium0.9%26
9
Prasugrel-hydrochloride0.7%22
10
Atorvastatin-calcium0.6%18
11
Bivalirudin0.6%17
12
Abciximab0.5%15
13
Warfarin0.5%15
14
Nitroglycerin0.4%12
15
Amiodarone-hydrochloride0.4%11

Taken alongside

1
Aspirin49.5%1,454
2
Gemfibrozil30.8%906
3
Heparin28.8%845
4
Clopidogrel-bisulfate7.5%220
5
Atorvastatin-calcium5.9%173
6
Ticagrelor3.8%113
7
Enoxaparin-sodium2.9%85
8
Nitroglycerin2.3%67
9
Metoprolol2.0%59
10
Simvastatin1.7%51
11
Furosemide1.7%51
12
Insulin1.6%48
13
Ramipril1.5%43
14
Isosorbide1.3%39
15
Bisoprolol-fumarate1.3%39

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tirofiban side effects

13.8% of tirofiban adverse event reports involve female patients and 23.1% involve male patients. The largest age group is adult at 76%. These figures reflect who reports side effects, not underlying risk.

Sex

Female13.8%
Male23.1%
Unknown63.1%

Age group

< 20.0%
2–110.5%
12–17<0.1%
18–6476.1%
65+23.3%

What is tirofiban used for

Conditions and purposes for which patients were taking tirofiban when the adverse event was reported.

Acute Coronary SyndromeAcute Myocardial InfarctionAngina PectorisAngina UnstableAngiogramAngioplastyAnticoagulant TherapyAnticoagulation Drug Level TherapeuticAntiplatelet TherapyAntithrombin IiiArterial StenosisArteriogram CoronaryArteriosclerosisAcute Coronary SyndromeAcute Myocardial Infarction

Showing 15 of 113 indications

Tirofiban brand names and reporting trend

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tirofiban with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.