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Tipranavir Side Effects

The most commonly reported side effects of tipranavir include nausea, vomiting, and cholelithiasis, based on 1,494 FDA adverse event reports from 2004 to 2025.

Tipranavir side effects

Percentages show how often each reaction appears relative to total reports for tipranavir.

1
Nausea15.7%235
2
Vomiting15.7%235
3
Cholelithiasis15.7%234
4
Schizophrenia15.6%233
5
Pneumonia15.5%232
6
Hypomania10.9%163
7
Psychotic Disorder10.6%159
8
Hepatic Enzyme Increased10.6%158
9
Hepatotoxicity10.6%158
10
Death10.5%157
11
Condition Aggravated10.5%157
12
Jaundice Cholestatic10.5%157
13
Blood Bilirubin Increased10.5%157
14
Off Label Use7.1%106
15
Oedema Peripheral6.4%96

These are voluntary reports and do not establish that tipranavir caused these reactions.

Report severity

92.0%Serious1,375 reports
49.4%Hospitalizations738 reports
22.2%Fatal331 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tipranavir drug interactions

Other drugs that appear in adverse event reports alongside tipranavir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ritonavir49.2%735
2
Tenofovir21.1%315
3
Olanzapine15.4%230
4
Quetiapine-fumarate15.3%229
5
Diazepam15.2%227
6
Trazodone-hydrochloride14.5%217
7
Carbamazepine14.5%217
8
Clonazepam14.3%213
9
Risperidone14.3%213
10
Enfuvirtide14.1%210
11
Acetaminophen13.6%203
12
Emtricitabine13.2%197
13
Procyclidine-hydrochloride12.7%189
14
Lamivudine11.5%172
15
Zidovudine11.3%169

Taken alongside

1
Enfuvirtide29.3%438
2
Ritonavir28.1%420
3
Lamivudine27.4%409
4
Tenofovir23.8%356
5
Abacavir22.6%338
6
Lopinavir16.1%241
7
Loperamide-hydrochloride15.5%232
8
Calcium-carbonate13.6%203
9
Lithium13.5%202
10
Lactulose13.3%199
11
Bisacodyl13.2%197
12
Nystatin13.1%195
13
Emtricitabine10.8%162
14
Sertraline-hydrochloride10.4%155
15
Zidovudine8.6%129

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tipranavir side effects

32.1% of tipranavir adverse event reports involve female patients and 55.8% involve male patients. The largest age group is adult at 91%. These figures reflect who reports side effects, not underlying risk.

Sex

Female32.1%
Male55.8%
Unknown12.1%

Age group

< 22.6%
2–110.3%
12–172.1%
18–6490.9%
65+4.1%

What is tipranavir used for

Conditions and purposes for which patients were taking tipranavir when the adverse event was reported.

Acquired Immunodeficiency SyndromeAntiretroviral TherapyAntiviral TreatmentAntiretroviral TherapyCerebral HaemorrhageDrug Exposure During PregnancyDrug LevelDrug Use For Unknown IndicationEnd Stage AidsExposure During PregnancyExposure During PregnancyFoetal Exposure During PregnancyHepatitis CHiv InfectionHiv Infection Cdc Category A3

Showing 15 of 31 indications

Tipranavir brand names and reporting trend

Tipranavir is sold under the brand name Aptivus.

Brand names

Aptivus908

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tipranavir with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.