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Tildrakizumab Side Effects

The most commonly reported side effects of tildrakizumab include product dose omission issue, death, and psoriasis, based on 2,574 FDA adverse event reports from 2018 to 2025. 11.0% of reports found the drug to be ineffective.

Tildrakizumab side effects

Percentages show how often each reaction appears relative to total reports for tildrakizumab.

1
Product Dose Omission Issue16.5%424
2
Drug Ineffective11.0%283
3
Death6.2%160
4
Psoriasis5.1%132
5
Off Label Use3.8%98
6
Condition Aggravated3.5%90
7
Self-medication3.0%78
8
Product Storage Error3.0%76
9
Pruritus2.7%70
10
Inappropriate Schedule Of Product Administration2.6%68
11
Rash2.6%66
12
Therapy Cessation2.6%66
13
Diarrhoea2.0%52
14
Urinary Tract Infection2.0%52
15
Pneumonia1.9%49

These are voluntary reports and do not establish that tildrakizumab caused these reactions.

Report severity

47.7%Serious1,228 reports
17.8%Hospitalizations457 reports
8.1%Fatal208 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tildrakizumab drug interactions

Other drugs that appear in adverse event reports alongside tildrakizumab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab2.1%54
2
Methotrexate1.8%47
3
Secukinumab1.6%40
4
Apremilast1.4%37
5
Ustekinumab1.0%27
6
Ixekizumab1.0%27
7
Risankizumab-rzaa1.0%25
8
Etanercept0.9%24
9
Guselkumab0.9%22
10
Certolizumab-pegol0.8%21
11
Infliximab0.7%17
12
Brodalumab0.5%12
13
Acitretin0.5%12
14
Bimekizumab-bkzx0.4%11
15
Cyclosporine0.3%8

Taken alongside

1
Aspirin4.2%108
2
Atorvastatin-calcium3.6%92
3
Metformin2.8%73
4
Amlodipine2.4%63
5
Levothyroxine-sodium2.2%57
6
Acetaminophen2.1%55
7
Omeprazole2.1%54
8
Betamethasone1.8%46
9
Methotrexate1.8%46
10
Metoprolol1.7%44
11
Calcipotriene1.7%44
12
Albuterol1.7%43
13
Rosuvastatin1.5%39
14
Ergocalciferol1.4%37
15
Apixaban1.4%36

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tildrakizumab side effects

44.7% of tildrakizumab adverse event reports involve female patients and 43.4% involve male patients. The largest age group is elderly at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.7%
Male43.4%
Unknown12.0%

Age group

< 20.4%
2–110.0%
12–170.2%
18–6445.6%
65+53.8%

What is tildrakizumab used for

Conditions and purposes for which patients were taking tildrakizumab when the adverse event was reported.

Alopecia ScarringAnal PruritusArthritisAsthmaBehcet^s SyndromeChronic Cutaneous Lupus ErythematosusCheilitis GranulomatosaChondrosarcomaChronic Lymphocytic LeukaemiaColitis UlcerativeCrohn^s DiseaseDermatitis AtopicDepressionDermatitis ContactEczema

Showing 15 of 49 indications

Tildrakizumab brand names and reporting trend

Tildrakizumab is sold under the brand name Ilumya.

Brand names

Ilumya1,234

Quarterly reports (20182025)

20182020202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tildrakizumab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.