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Tiagabine Side Effects

The most commonly reported side effects of tiagabine include convulsion, confusional state, and dizziness, based on 1,588 FDA adverse event reports from 2004 to 2025. 6.7% of reports found the drug to be ineffective.

Tiagabine side effects

Percentages show how often each reaction appears relative to total reports for tiagabine.

1
Convulsion10.1%161
2
Drug Ineffective6.7%106
3
Confusional State4.8%76
4
Dizziness4.5%71
5
Loss Of Consciousness4.4%70
6
Completed Suicide4.0%64
7
Seizure4.0%63
8
Drug Ineffective3.8%61
9
Tremor3.7%59
10
Drug Interaction3.5%56
11
Nausea3.3%52
12
Fall3.3%52
13
Dizziness3.2%51
14
Off Label Use3.2%51
15
Anxiety3.1%50

These are voluntary reports and do not establish that tiagabine caused these reactions.

Report severity

79.4%Serious1,261 reports
34.3%Hospitalizations545 reports
8.6%Fatal137 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tiagabine drug interactions

Other drugs that appear in adverse event reports alongside tiagabine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Gabapentin9.1%145
2
Lamotrigine8.9%142
3
Levetiracetam7.8%124
4
Quetiapine-fumarate6.5%103
5
Phenytoin6.3%100
6
Topiramate4.9%78
7
Fentanyl4.8%77
8
Carbamazepine4.6%73
9
Clonazepam4.4%70
10
Lacosamide4.3%68
11
Sodium-oxybate4.2%66
12
Zolpidem-tartrate3.3%53
13
Vigabatrin3.3%52
14
Oxcarbazepine3.2%51
15
Pregabalin2.9%46

Taken alongside

1
Clonazepam14.2%225
2
Gabapentin13.4%213
3
Acetaminophen12.5%199
4
Levothyroxine-sodium9.4%149
5
Oxycodone8.0%127
6
Hydrocodone7.4%117
7
Lamotrigine7.4%117
8
Topiramate7.2%115
9
Trazodone-hydrochloride6.7%107
10
Lorazepam6.6%105
11
Escitalopram-oxalate6.6%105
12
Aspirin6.5%104
13
Alprazolam6.3%100
14
Atorvastatin-calcium6.2%98
15
Venlafaxine6.1%97

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tiagabine side effects

54.6% of tiagabine adverse event reports involve female patients and 38.0% involve male patients. The largest age group is adult at 83%. These figures reflect who reports side effects, not underlying risk.

Sex

Female54.6%
Male38.0%
Unknown7.4%

Age group

< 21.1%
2–111.7%
12–173.0%
18–6482.6%
65+11.6%

What is tiagabine used for

Conditions and purposes for which patients were taking tiagabine when the adverse event was reported.

Affective DisorderAggressionAgitationAgoraphobiaAmnesiaAngerAnticonvulsant Drug Level TherapeuticAntidepressant TherapyAnxietyAnxiety DisorderArthralgiaAttention Deficit/hyperactivity DisorderAnxietyAutism Spectrum DisorderBack Pain

Showing 15 of 128 indications

Tiagabine brand names and reporting trend

Tiagabine is sold under the brand name Tiagabine Hydrochloride.

Brand names

Tiagabine Hydrochloride6

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tiagabine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.