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Thonzonium Side Effects

The most commonly reported side effects of thonzonium include optic neuritis, off label use, and leukopenia, based on 16 FDA adverse event reports from 2004 to 2025.

Thonzonium side effects

Percentages show how often each reaction appears relative to total reports for thonzonium.

1
Optic Neuritis12.5%2
2
Off Label Use12.5%2
3
Leukopenia6.3%1
4
Ear Pruritus6.3%1
5
Renal Disorder6.3%1
6
No Adverse Event6.3%1
7
Incorrect Route Of Drug Administration6.3%1
8
Accidental Exposure To Product6.3%1
9
Multiple Sclerosis Relapse6.3%1
10
Tongue Discomfort6.3%1
11
Retching6.3%1
12
Vomiting6.3%1
13
Medication Error6.3%1
14
Tooth Disorder6.3%1
15
Throat Irritation6.3%1

These are voluntary reports and do not establish that thonzonium caused these reactions.

Report severity

31.3%Serious5 reports
0.0%Hospitalizations0 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Thonzonium drug interactions

Other drugs that appear in adverse event reports alongside thonzonium. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Colistin-sulfate81.3%13
2
Hydrocortisone81.3%13
3
Neomycin-sulfate81.3%13
4
Esomeprazole12.5%2
5
Levetiracetam12.5%2
6
Lipase12.5%2
7
Pancrelipase-amylase12.5%2
8
Protease12.5%2
9
Ascorbic-acid12.5%2
10
Polyethylene-glycol-335012.5%2
11
Potassium-chloride12.5%2
12
Sodium-ascorbate12.5%2
13
Sodium-chloride12.5%2
14
Sodium-sulfate12.5%2
15
Ganciclovir12.5%2

Taken alongside

1
Zolpidem-tartrate18.8%3
2
Colistin-sulfate18.8%3
3
Hydrocortisone18.8%3
4
Neomycin-sulfate18.8%3
5
Vancomycin12.5%2
6
Paroxetine12.5%2
7
Hydroxyzine12.5%2
8
Sulfamethoxazole12.5%2
9
Metformin12.5%2
10
Azelastine12.5%2
11
Azithromycin12.5%2
12
Acetaminophen12.5%2
13
Hydrocodone12.5%2
14
Levothyroxine-sodium12.5%2
15
Montelukast-sodium12.5%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports thonzonium side effects

37.5% of thonzonium adverse event reports involve female patients and 37.5% involve male patients. The largest age group is adult at 71%. These figures reflect who reports side effects, not underlying risk.

Sex

Female37.5%
Male37.5%
Unknown25.0%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6471.4%
65+28.6%

What is thonzonium used for

Conditions and purposes for which patients were taking thonzonium when the adverse event was reported.

Cystic FibrosisEar InfectionEar InfectionInflammationIngrowing NailProduct Used For Unknown IndicationProphylaxisPseudomonas InfectionProduct Used For Unknown IndicationRespiratory Tract InfectionSurgery

Thonzonium brand names and reporting trend

Thonzonium is sold under the brand name Coly-mycin S.

Brand names

Coly-mycin S1

Quarterly reports (20042025)

20042025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking thonzonium with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.