OpenClaim

Tesamorelin Side Effects

The most commonly reported side effects of tesamorelin include product dose omission issue, arthralgia, and injection site pain, based on 3,362 FDA adverse event reports from 2009 to 2025. 5.2% of reports found the drug to be ineffective.

Tesamorelin side effects

Percentages show how often each reaction appears relative to total reports for tesamorelin.

1
Product Dose Omission Issue8.3%280
2
Arthralgia6.7%226
3
Injection Site Pain5.9%197
4
Drug Ineffective5.2%175
5
Incorrect Dose Administered5.1%172
6
Weight Increased5.0%167
7
Injection Site Bruising4.4%147
8
Pain In Extremity4.2%140
9
Peripheral Swelling3.7%126
10
Injection Site Pruritus3.7%123
11
Product Preparation Issue3.6%120
12
Hypoaesthesia3.0%101
13
Blood Glucose Increased2.9%96
14
Myalgia2.9%96
15
Fatigue2.7%91

These are voluntary reports and do not establish that tesamorelin caused these reactions.

Report severity

23.3%Serious782 reports
8.6%Hospitalizations290 reports
2.3%Fatal78 reports

Seriousness is determined by the reporter, not by OpenClaim.

Tesamorelin drug interactions

Other drugs that appear in adverse event reports alongside tesamorelin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Tenofovir0.6%20
2
Emtricitabine0.6%19
3
Rilpivirine0.2%8
4
Somatropin0.2%6
5
Cabotegravir0.2%6
6
Dolutegravir0.2%6
7
Efavirenz0.1%5
8
Testosterone0.1%4
9
Semaglutide0.1%4
10
Etravirine<0.1%3
11
Cobicistat<0.1%3
12
Elvitegravir<0.1%3
13
Dupilumab<0.1%3
14
Dulaglutide<0.1%3
15
Lenacapavir<0.1%3

Taken alongside

1
Tenofovir10.8%364
2
Emtricitabine10.6%356
3
Dolutegravir5.1%172
4
Atorvastatin-calcium5.1%171
5
Testosterone5.0%169
6
Gabapentin4.3%144
7
Lisinopril4.1%137
8
Aspirin4.0%134
9
Metformin3.7%125
10
Ergocalciferol3.7%124
11
Darunavir3.5%116
12
Cobicistat3.4%114
13
Omeprazole3.3%110
14
Ritonavir3.2%109
15
Rosuvastatin3.2%107

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports tesamorelin side effects

7.7% of tesamorelin adverse event reports involve female patients and 37.4% involve male patients. The largest age group is adult at 91%. These figures reflect who reports side effects, not underlying risk.

Sex

Female7.7%
Male37.4%
Unknown54.9%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6491.4%
65+8.6%

What is tesamorelin used for

Conditions and purposes for which patients were taking tesamorelin when the adverse event was reported.

Abdominal Fat ApronAbdominal Pain LowerAcquired Immunodeficiency SyndromeAlpha-1 Anti-trypsin DeficiencyAsymptomatic Hiv InfectionAutoimmune DisorderAbdominal DistensionAcquired Generalised LipodystrophyAdverse ReactionBody Fat DisorderBody Mass IndexCachexiaCentral ObesityCerebral ToxoplasmosisCognitive Disorder

Showing 15 of 62 indications

Tesamorelin brand names and reporting trend

Tesamorelin is sold under the brand name Egrifta.

Brand names

Egrifta8

Quarterly reports (20092025)

200920122016202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking tesamorelin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.