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Terlipressin Side Effects

The most commonly reported side effects of terlipressin include electrocardiogram qt prolonged, renal impairment, and ascites, based on 303 FDA adverse event reports from 2004 to 2025. 11.9% of reports found the drug to be ineffective.

Terlipressin side effects

Percentages show how often each reaction appears relative to total reports for terlipressin.

1
Drug Ineffective11.9%36
2
Electrocardiogram Qt Prolonged7.3%22
3
Renal Impairment6.6%20
4
Ascites5.9%18
5
Off Label Use5.9%18
6
Diarrhoea5.3%16
7
Hepatic Encephalopathy5.3%16
8
Multiple Organ Dysfunction Syndrome5.3%16
9
Product Use In Unapproved Indication5.0%15
10
Acute Kidney Injury4.3%13
11
Haemoglobin Decreased4.0%12
12
Liver Disorder4.0%12
13
Lower Respiratory Tract Infection4.0%12
14
Drug Interaction4.0%12
15
Toxicity To Various Agents4.0%12

These are voluntary reports and do not establish that terlipressin caused these reactions.

Report severity

94.1%Serious285 reports
50.8%Hospitalizations154 reports
30.4%Fatal92 reports

Seriousness is determined by the reporter, not by OpenClaim.

Terlipressin drug interactions

Other drugs that appear in adverse event reports alongside terlipressin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Epinephrine10.2%31
2
Vancomycin6.6%20
3
Ribavirin5.9%18
4
Hydrocortisone5.6%17
5
Ciprofloxacin5.3%16
6
Sofosbuvir5.3%16
7
Meropenem4.3%13
8
Furosemide4.0%12
9
Olanzapine3.6%11
10
Haloperidol3.6%11
11
Spironolactone3.3%10
12
Fluconazole3.0%9
13
Daptomycin3.0%9
14
Simeprevir-sodium3.0%9
15
Ondansetron3.0%9

Taken alongside

1
Furosemide22.1%67
2
Omeprazole19.8%60
3
Spironolactone18.5%56
4
Acetaminophen17.5%53
5
Lactulose14.5%44
6
Meropenem13.9%42
7
Thiamine12.5%38
8
Epinephrine12.2%37
9
Ceftriaxone-sodium11.2%34
10
Metronidazole10.9%33
11
Vancomycin8.9%27
12
Rifaximin8.9%27
13
Folic-acid7.9%24
14
Albumin-human7.9%24
15
Insulin7.3%22

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports terlipressin side effects

31.4% of terlipressin adverse event reports involve female patients and 56.4% involve male patients. The largest age group is adult at 64%. These figures reflect who reports side effects, not underlying risk.

Sex

Female31.4%
Male56.4%
Unknown12.2%

Age group

< 21.9%
2–111.9%
12–171.6%
18–6464.2%
65+30.4%

What is terlipressin used for

Conditions and purposes for which patients were taking terlipressin when the adverse event was reported.

Acute Kidney InjuryAortic DissectionAtrial FibrillationBlood Pressure MeasurementCardiac FailureCardiogenic ShockChronic Hepatic FailureCirculatory CollapseDistributive ShockGastric Varices HaemorrhageGastrointestinal HaemorrhageGastric Varices HaemorrhageGastrointestinal HaemorrhageHaemostasisHepatorenal Syndrome

Showing 15 of 57 indications

Terlipressin brand names and reporting trend

Terlipressin is sold under the brand name Terlivaz.

Brand names

Terlivaz342

Quarterly reports (20042025)

2005201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking terlipressin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.