OpenClaim

Terbinafine Side Effects

The most commonly reported side effects of terbinafine include rash, pruritus, and fatigue, based on 16,472 FDA adverse event reports from 2004 to 2025. 7.6% of reports found the drug to be ineffective.

Terbinafine side effects

Percentages show how often each reaction appears relative to total reports for terbinafine.

1
Drug Ineffective7.6%1,250
2
Rash4.1%678
3
Pruritus3.6%601
4
Fatigue3.5%584
5
Nausea3.2%530
6
Pain3.1%506
7
Off Label Use3.0%497
8
Ageusia2.8%459
9
Headache2.7%444
10
Diarrhoea2.5%417
11
Dyspnoea2.2%368
12
Arthralgia2.1%350
13
Weight Decreased2.1%345
14
Anxiety2.1%342
15
Product Use In Unapproved Indication2.1%340

These are voluntary reports and do not establish that terbinafine caused these reactions.

Report severity

75.1%Serious12,366 reports
26.2%Hospitalizations4,317 reports
5.1%Fatal844 reports

Seriousness is determined by the reporter, not by OpenClaim.

Terbinafine drug interactions

Other drugs that appear in adverse event reports alongside terbinafine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Voriconazole2.2%365
2
Sodium-oxybate2.1%349
3
Omeprazole1.8%300
4
Amphotericin-b1.8%289
5
Esomeprazole1.5%252
6
Dupilumab1.4%238
7
Adalimumab1.3%217
8
Lenalidomide1.3%211
9
Lansoprazole1.3%208
10
Pantoprazole-sodium1.2%201
11
Itraconazole1.2%194
12
Methotrexate1.1%184
13
Prednisone0.9%156
14
Fluconazole0.9%155
15
Tacrolimus0.9%149

Taken alongside

1
Acetaminophen9.1%1,503
2
Aspirin9.0%1,476
3
Ergocalciferol7.1%1,173
4
Atorvastatin-calcium7.0%1,148
5
Omeprazole6.4%1,049
6
Amlodipine6.1%997
7
Levothyroxine-sodium6.1%997
8
Albuterol5.6%925
9
Metformin5.5%906
10
Prednisone5.4%884
11
Furosemide5.3%869
12
Gabapentin5.1%847
13
Lisinopril4.8%793
14
Ibuprofen4.6%752
15
Fluticasone4.4%727

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports terbinafine side effects

46.3% of terbinafine adverse event reports involve female patients and 43.6% involve male patients. The largest age group is adult at 64%. These figures reflect who reports side effects, not underlying risk.

Sex

Female46.3%
Male43.6%
Unknown10.1%

Age group

< 20.2%
2–111.2%
12–171.6%
18–6463.7%
65+33.2%

What is terbinafine used for

Conditions and purposes for which patients were taking terbinafine when the adverse event was reported.

Abnormal FaecesAbscessAcarodermatitisAccidental ExposureAccidental Exposure To ProductAcneActinic KeratosisAdverse ReactionAlopeciaAlternaria InfectionAnalgesic TherapyAngular CheilitisAnimal BiteAnti-infective TherapyAntibiotic Level

Showing 15 of 437 indications

Terbinafine brand names and reporting trend

Terbinafine is sold under the brand name Lamisil.

Brand names

Lamisil10,970

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking terbinafine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.