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Telaprevir Side Effects

The most commonly reported side effects of telaprevir include fatigue, nausea, and anaemia, based on 21,693 FDA adverse event reports from 2008 to 2025.

Telaprevir side effects

Percentages show how often each reaction appears relative to total reports for telaprevir.

1
Fatigue13.4%2,900
2
Nausea12.3%2,658
3
Anaemia12.1%2,622
4
Rash11.0%2,391
5
Pruritus9.2%1,988
6
Headache6.4%1,386
7
Diarrhoea6.0%1,294
8
Vomiting5.9%1,275
9
Anorectal Discomfort5.1%1,117
10
Decreased Appetite4.7%1,009
11
Pyrexia4.6%1,002
12
Asthenia4.6%996
13
Dyspnoea4.4%961
14
Insomnia4.3%923
15
Influenza Like Illness4.1%879

These are voluntary reports and do not establish that telaprevir caused these reactions.

Report severity

32.8%Serious7,126 reports
15.3%Hospitalizations3,320 reports
2.2%Fatal482 reports

Seriousness is determined by the reporter, not by OpenClaim.

Telaprevir drug interactions

Other drugs that appear in adverse event reports alongside telaprevir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ribavirin53.7%11,652
2
Peginterferon46.3%10,048
3
Ropeginterferon-alfa-2b-njft3.1%670
4
Boceprevir1.2%250
5
Epoetin0.4%82
6
Sofosbuvir0.4%80
7
Tacrolimus0.4%76
8
Mycophenolate0.2%53
9
Cyclosporine0.2%52
10
Raltegravir-potassium0.2%50
11
Tenofovir0.2%50
12
Interferon0.2%47
13
Atazanavir-sulfate0.2%42
14
Emtricitabine0.2%42
15
Ritonavir0.2%38

Taken alongside

1
Ribavirin36.9%7,999
2
Peginterferon32.4%7,028
3
Ropeginterferon-alfa-2b-njft3.4%735
4
Lisinopril2.8%602
5
Acetaminophen2.2%477
6
Omeprazole2.2%471
7
Levothyroxine-sodium1.8%399
8
Metformin1.8%380
9
Amlodipine1.7%373
10
Hydrochlorothiazide1.7%361
11
Ibuprofen1.5%330
12
Aspirin1.5%328
13
Citalopram-hydrobromide1.3%292
14
Alprazolam1.3%280
15
Zolpidem-tartrate1.2%260

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports telaprevir side effects

39.9% of telaprevir adverse event reports involve female patients and 49.8% involve male patients. The largest age group is adult at 93%. These figures reflect who reports side effects, not underlying risk.

Sex

Female39.9%
Male49.8%
Unknown10.4%

Age group

< 2<0.1%
2–11<0.1%
12–17<0.1%
18–6492.6%
65+7.3%

What is telaprevir used for

Conditions and purposes for which patients were taking telaprevir when the adverse event was reported.

Acute Hepatitis CAcute Hiv InfectionAdrenogenital SyndromeAntiviral TreatmentAntiviral TreatmentChronic HepatitisChronic Hepatitis BChronic Hepatitis CComaComa HepaticCryoglobulinaemiaChronic Hepatitis CCryoglobulinaemiaDepressionDisease Recurrence

Showing 15 of 56 indications

Telaprevir brand names and reporting trend

Telaprevir is sold under the brand name Incivek.

Brand names

Incivek7,170

Quarterly reports (20082025)

2008201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking telaprevir with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.