OpenClaim

Talquetamab Side Effects

The most commonly reported side effects of talquetamab include cytokine release syndrome, dysgeusia, and weight decreased, based on 1,620 FDA adverse event reports from 2022 to 2025.

Talquetamab side effects

Percentages show how often each reaction appears relative to total reports for talquetamab.

1
Cytokine Release Syndrome23.7%384
2
Dysgeusia9.7%157
3
Weight Decreased9.3%150
4
Immune Effector Cell-associated Neurotoxicity Syndrome8.0%129
5
Ageusia7.8%126
6
Skin Exfoliation7.7%125
7
Plasma Cell Myeloma6.4%104
8
Dry Mouth6.3%102
9
Rash5.6%90
10
Pyrexia5.5%89
11
Off Label Use5.2%84
12
Nail Disorder5.1%82
13
Death4.4%72
14
Neutropenia4.3%70
15
Fatigue4.3%70

These are voluntary reports and do not establish that talquetamab caused these reactions.

Report severity

69.6%Serious1,127 reports
26.1%Hospitalizations423 reports
10.6%Fatal171 reports

Seriousness is determined by the reporter, not by OpenClaim.

Talquetamab drug interactions

Other drugs that appear in adverse event reports alongside talquetamab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Daratumumab9.3%151
2
Teclistamab-cqyv8.8%143
3
Dexamethasone8.3%134
4
Pomalidomide6.9%111
5
Lenalidomide6.7%108
6
Carfilzomib4.9%79
7
Bortezomib4.3%70
8
Cyclophosphamide3.0%49
9
Fludarabine-phosphate1.7%28
10
Selinexor1.5%24
11
Etoposide1.4%22
12
Cisplatin1.4%22
13
Elotuzumab1.4%22
14
Thalidomide1.3%21
15
Doxorubicin-hydrochloride1.2%19

Taken alongside

1
Acyclovir9.9%161
2
Acetaminophen5.0%81
3
Dexamethasone4.7%76
4
Sulfamethoxazole3.3%53
5
Trimethoprim3.0%49
6
Allopurinol3.0%49
7
Aspirin2.9%47
8
Ondansetron2.7%43
9
Omeprazole2.6%42
10
Pantoprazole-sodium2.5%40
11
Oxycodone2.3%38
12
Apixaban2.1%34
13
Amlodipine1.9%30
14
Diphenhydramine1.8%29
15
Atorvastatin-calcium1.7%27

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports talquetamab side effects

24.5% of talquetamab adverse event reports involve female patients and 32.2% involve male patients. The largest age group is elderly at 57%. These figures reflect who reports side effects, not underlying risk.

Sex

Female24.5%
Male32.2%
Unknown43.3%

Age group

< 20.0%
2–110.0%
12–170.3%
18–6442.8%
65+56.9%

What is talquetamab used for

Conditions and purposes for which patients were taking talquetamab when the adverse event was reported.

Bronchopulmonary AspergillosisMultiple SclerosisNeoplasm MalignantNeutropeniaPlasma Cell LeukaemiaPlasma Cell MyelomaPlasma Cell Myeloma RecurrentPlasma Cell Myeloma RefractoryPlasmablastic LymphomaPlasmacytomaPrimary AmyloidosisProduct Used For Unknown Indication

Talquetamab brand names and reporting trend

Talquetamab is sold under the brand name Talvey.

Brand names

Talvey838

Quarterly reports (20222025)

202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking talquetamab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.