OpenClaim

Sunvozertinib Side Effects

The most commonly reported side effects of sunvozertinib include diarrhoea, decreased appetite, and rash, based on 23 FDA adverse event reports from 2024 to 2025. 4.3% of reports found the drug to be ineffective.

Sunvozertinib side effects

Percentages show how often each reaction appears relative to total reports for sunvozertinib.

1
Diarrhoea17.4%4
2
Decreased Appetite13.0%3
3
Rash13.0%3
4
Platelet Count Decreased13.0%3
5
Paronychia8.7%2
6
Blood Creatine Phosphokinase Increased8.7%2
7
Pneumonitis8.7%2
8
Anaemia8.7%2
9
Mouth Ulceration8.7%2
10
Gastric Perforation8.7%2
11
Drug Ineffective4.3%1
12
Disease Progression4.3%1
13
Gastrointestinal Haemorrhage4.3%1
14
Sepsis4.3%1
15
Shock4.3%1

These are voluntary reports and do not establish that sunvozertinib caused these reactions.

Report severity

100.0%Serious23 reports
91.3%Hospitalizations21 reports
8.7%Fatal2 reports

Seriousness is determined by the reporter, not by OpenClaim.

Sunvozertinib drug interactions

Other drugs that appear in adverse event reports alongside sunvozertinib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Bevacizumab8.7%2
2
Erlotinib-hydrochloride4.3%1
3
Pemetrexed4.3%1
4
Dacomitinib4.3%1

Taken alongside

1
Capecitabine4.3%1
2
Loperamide-hydrochloride4.3%1
3
Fluticasone4.3%1
4
Umeclidinium-bromide4.3%1
5
Vilanterol-trifenatate4.3%1
6
Levofloxacin4.3%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports sunvozertinib side effects

43.5% of sunvozertinib adverse event reports involve female patients and 56.5% involve male patients. The largest age group is elderly at 55%. These figures reflect who reports side effects, not underlying risk.

Sex

Female43.5%
Male56.5%
Unknown0.0%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6445.0%
65+55.0%

What is sunvozertinib used for

Conditions and purposes for which patients were taking sunvozertinib when the adverse event was reported.

Lung AdenocarcinomaLung Adenocarcinoma Stage IvLung Neoplasm MalignantMetastases To Central Nervous SystemMetastases To PleuraNeoplasm MalignantNon-small Cell Lung Cancer

Sunvozertinib brand names and reporting trend

Sunvozertinib is sold under the brand name Zegfrovy.

Brand names

Zegfrovy26

Quarterly reports (20242025)

20242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking sunvozertinib with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.