OpenClaim

Sulfapyridine Side Effects

The most commonly reported side effects of sulfapyridine include pneumonia, rheumatoid arthritis, and pyrexia, based on 720 FDA adverse event reports from 2004 to 2025. 3.6% of reports found the drug to be ineffective.

Sulfapyridine side effects

Percentages show how often each reaction appears relative to total reports for sulfapyridine.

1
Pneumonia6.3%45
2
Rheumatoid Arthritis4.3%31
3
Drug Ineffective3.6%26
4
Pyrexia3.3%24
5
Interstitial Lung Disease2.9%21
6
Lymphoproliferative Disorder2.8%20
7
Condition Aggravated2.6%19
8
Off Label Use2.6%19
9
Diarrhoea2.4%17
10
Hepatic Function Abnormal2.1%15
11
Cerebral Infarction1.9%14
12
Cellulitis1.9%14
13
Urinary Tract Infection1.8%13
14
Pancytopenia1.8%13
15
Infection1.8%13

These are voluntary reports and do not establish that sulfapyridine caused these reactions.

Report severity

97.6%Serious703 reports
58.6%Hospitalizations422 reports
11.8%Fatal85 reports

Seriousness is determined by the reporter, not by OpenClaim.

Sulfapyridine drug interactions

Other drugs that appear in adverse event reports alongside sulfapyridine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Methotrexate18.8%135
2
Adalimumab17.9%129
3
Prednisolone13.9%100
4
Golimumab11.4%82
5
Certolizumab-pegol8.2%59
6
Tacrolimus7.9%57
7
Tocilizumab7.9%57
8
Etanercept6.7%48
9
Infliximab6.0%43
10
Abatacept5.7%41
11
Prednisone4.2%30
12
Tofacitinib3.6%26
13
Mesalamine2.5%18
14
Methylprednisolone1.7%12
15
Azathioprine1.4%10

Taken alongside

1
Prednisolone31.4%226
2
Methotrexate16.7%120
3
Prednisone9.4%68
4
Celecoxib8.6%62
5
Folic-acid7.6%55
6
Lansoprazole6.9%50
7
Tacrolimus5.8%42
8
Amlodipine5.0%36
9
Diclofenac4.9%35
10
Isoniazid3.6%26
11
Esomeprazole3.6%26
12
Furosemide3.3%24
13
Famotidine3.2%23
14
Alendronate-sodium3.1%22
15
Aspirin3.1%22

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports sulfapyridine side effects

61.9% of sulfapyridine adverse event reports involve female patients and 32.2% involve male patients. The largest age group is elderly at 57%. These figures reflect who reports side effects, not underlying risk.

Sex

Female61.9%
Male32.2%
Unknown5.8%

Age group

< 20.5%
2–110.7%
12–170.5%
18–6441.6%
65+56.7%

What is sulfapyridine used for

Conditions and purposes for which patients were taking sulfapyridine when the adverse event was reported.

Analgesic TherapyAnkylosing SpondylitisArthralgiaArthritisArthritis ReactiveAtypical Mycobacterial InfectionAcute Febrile Neutrophilic DermatosisBehcet^s SyndromeColitis IschaemicColitis UlcerativeCrohn's DiseaseCrohn^s DiseaseDisseminated TuberculosisDrug TherapyDrug Use For Unknown Indication

Showing 15 of 41 indications

Sulfapyridine brand names and reporting trend

Sulfapyridine is sold under the brand name Sulfapyridine.

Brand names

Sulfapyridine792

Quarterly reports (20042025)

20042010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking sulfapyridine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.