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Sulfamerazine Side Effects

The most commonly reported side effects of sulfamerazine include drug hypersensitivity, pain, and off label use, based on 250 FDA adverse event reports from 2004 to 2025. 4.0% of reports found the drug to be ineffective.

Sulfamerazine side effects

Percentages show how often each reaction appears relative to total reports for sulfamerazine.

1
Drug Hypersensitivity17.2%43
2
Pain4.8%12
3
Off Label Use4.8%12
4
Dyspnoea4.4%11
5
Fatigue4.4%11
6
Rash4.4%11
7
Leukopenia4.0%10
8
Thrombocytopenia4.0%10
9
Nausea4.0%10
10
Drug Ineffective4.0%10
11
Arthralgia3.6%9
12
Injection Site Pain3.2%8
13
Anxiety3.2%8
14
Urticaria3.2%8
15
Vomiting3.2%8

These are voluntary reports and do not establish that sulfamerazine caused these reactions.

Report severity

68.0%Serious170 reports
34.8%Hospitalizations87 reports
11.6%Fatal29 reports

Seriousness is determined by the reporter, not by OpenClaim.

Sulfamerazine drug interactions

Other drugs that appear in adverse event reports alongside sulfamerazine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sulfadiazine30.0%75
2
Adalimumab14.0%35
3
Penicillin6.8%17
4
Trimethoprim6.8%17
5
Gemcitabine5.6%14
6
Ondansetron5.6%14
7
Irinotecan-hydrochloride5.2%13
8
Oxaliplatin4.8%12
9
Amphotericin-b4.8%12
10
Dimenhydrinate4.8%12
11
Loperamide-hydrochloride4.8%12
12
Dextrose4.8%12
13
Sodium-chloride4.8%12
14
Methotrexate4.8%12
15
Etanercept4.8%12

Taken alongside

1
Sulfadiazine49.6%124
2
Prednisone11.6%29
3
Aspirin10.0%25
4
Omeprazole10.0%25
5
Acetaminophen10.0%25
6
Folic-acid8.4%21
7
Levothyroxine-sodium8.0%20
8
Amlodipine8.0%20
9
Sulfamethazine7.6%19
10
Calcium7.6%19
11
Trisulfapyrimidines-sulfadiazine7.2%18
12
Gabapentin6.4%16
13
Ergocalciferol6.4%16
14
Lisinopril6.4%16
15
Ibuprofen6.4%16

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports sulfamerazine side effects

61.2% of sulfamerazine adverse event reports involve female patients and 32.4% involve male patients. The largest age group is adult at 55%. These figures reflect who reports side effects, not underlying risk.

Sex

Female61.2%
Male32.4%
Unknown6.4%

Age group

< 21.8%
2–113.6%
12–177.7%
18–6455.4%
65+31.5%

What is sulfamerazine used for

Conditions and purposes for which patients were taking sulfamerazine when the adverse event was reported.

Antifungal ProphylaxisBronchitisCystic FibrosisCystitisCoughDiverticulitisDrug Use For Unknown IndicationFolliculitisHypertensionHypersensitivityHypertensionImmunosuppressionInflammationInjection Site MassIntraocular Pressure Test

Showing 15 of 30 indications

Sulfamerazine brand names and reporting trend

Sulfamerazine is sold under the brand name Lantrisul.

Brand names

Lantrisul44

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking sulfamerazine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.