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Succimer Side Effects

The most commonly reported side effects of succimer include off label use, product availability issue, and no adverse event, based on 73 FDA adverse event reports from 2006 to 2025.

Succimer side effects

Percentages show how often each reaction appears relative to total reports for succimer.

1
Off Label Use31.5%23
2
Product Availability Issue12.3%9
3
No Adverse Event6.8%5
4
Weight Increased6.8%5
5
Skin Striae5.5%4
6
Hypertension5.5%4
7
Arthralgia4.1%3
8
Pain4.1%3
9
Headache4.1%3
10
Arthralgia4.1%3
11
Condition Aggravated4.1%3
12
Cushingoid4.1%3
13
Hypocalcaemia2.7%2
14
Wrong Drug Administered2.7%2
15
Arrhythmia2.7%2

These are voluntary reports and do not establish that succimer caused these reactions.

Report severity

50.7%Serious37 reports
17.8%Hospitalizations13 reports
4.1%Fatal3 reports

Seriousness is determined by the reporter, not by OpenClaim.

Succimer drug interactions

Other drugs that appear in adverse event reports alongside succimer. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-oxybate20.5%15
2
Methylprednisolone5.5%4
3
Calcium4.1%3
4
Edetate-calcium-disodium4.1%3
5
Prednisone4.1%3
6
Digoxin2.7%2
7
Amoxicillin2.7%2
8
Alendronate-sodium2.7%2
9
Ibandronate-sodium2.7%2
10
Risedronate-sodium2.7%2
11
Famotidine2.7%2
12
Ergocalciferol2.7%2
13
Buspirone-hydrochloride2.7%2
14
Propofol2.7%2
15
Dimercaprol2.7%2

Taken alongside

1
Ergocalciferol20.5%15
2
Ascorbic-acid12.3%9
3
Cyanocobalamin12.3%9
4
Cholestyramine12.3%9
5
Clonazepam11.0%8
6
Hydrocortisone11.0%8
7
Bupropion11.0%8
8
Acetaminophen9.6%7
9
Fluconazole9.6%7
10
Naltrexone9.6%7
11
Azithromycin9.6%7
12
Progesterone9.6%7
13
Hydrocodone6.8%5
14
Vitamin-e6.8%5
15
Fish6.8%5

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports succimer side effects

56.2% of succimer adverse event reports involve female patients and 37.0% involve male patients. The largest age group is adult at 41%. These figures reflect who reports side effects, not underlying risk.

Sex

Female56.2%
Male37.0%
Unknown6.8%

Age group

< 22.3%
2–1136.4%
12–176.8%
18–6440.9%
65+13.6%

What is succimer used for

Conditions and purposes for which patients were taking succimer when the adverse event was reported.

Blood Lead IncreasedChelation TherapyDrug Use For Unknown IndicationExposure To LeadHepato-lenticular DegenerationMetal PoisoningManganese IncreasedMetal PoisoningProduct Used For Unknown IndicationProduct Used For Unknown IndicationRadiation InjuryRenal ScanUnevaluable Event

Succimer brand names and reporting trend

Succimer is sold under the brand name Chemet.

Brand names

Chemet36

Quarterly reports (20062025)

200620102025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking succimer with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.