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Streptozocin Side Effects

The most commonly reported side effects of streptozocin include malignant neoplasm progression, product use in unapproved indication, and pancreatic neuroendocrine tumour, based on 227 FDA adverse event reports from 2004 to 2025. 13.2% of reports found the drug to be ineffective.

Streptozocin side effects

Percentages show how often each reaction appears relative to total reports for streptozocin.

1
Malignant Neoplasm Progression21.6%49
2
Product Use In Unapproved Indication14.1%32
3
Drug Ineffective13.2%30
4
Pancreatic Neuroendocrine Tumour13.2%30
5
Off Label Use12.8%29
6
Hypoglycaemia12.8%29
7
Fatigue12.3%28
8
Nausea11.9%27
9
Disease Progression8.4%19
10
Toxicity To Various Agents7.9%18
11
Weight Decreased7.9%18
12
Decreased Appetite7.5%17
13
Nephropathy Toxic7.5%17
14
Chronic Kidney Disease7.5%17
15
Cardiac Failure7.0%16

These are voluntary reports and do not establish that streptozocin caused these reactions.

Report severity

94.7%Serious215 reports
40.1%Hospitalizations91 reports
22.9%Fatal52 reports

Seriousness is determined by the reporter, not by OpenClaim.

Streptozocin drug interactions

Other drugs that appear in adverse event reports alongside streptozocin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Fluorouracil37.0%84
2
Everolimus31.7%72
3
Doxorubicin-hydrochloride29.1%66
4
Octreotide-acetate20.7%47
5
Capecitabine16.7%38
6
Lutetium12.8%29
7
Lanreotide-acetate12.3%28
8
Sunitinib-malate10.6%24
9
Etoposide10.1%23
10
Cisplatin8.4%19
11
Temozolomide8.4%19
12
Carboplatin8.4%19
13
Dexamethasone7.0%16
14
Dacarbazine6.2%14
15
Oxaliplatin5.3%12

Taken alongside

1
Doxorubicin-hydrochloride6.2%14
2
Fluorouracil6.2%14
3
Carisoprodol6.2%14
4
Lansoprazole5.3%12
5
Everolimus4.8%11
6
Insulin4.8%11
7
Bisoprolol-fumarate4.0%9
8
Dexamethasone3.5%8
9
Sunitinib-malate3.5%8
10
Lanreotide-acetate3.5%8
11
Edoxaban3.5%8
12
Octreotide-acetate3.1%7
13
Sodium-chloride2.6%6
14
Cisplatin2.2%5
15
Acetaminophen2.2%5

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports streptozocin side effects

35.7% of streptozocin adverse event reports involve female patients and 48.5% involve male patients. The largest age group is adult at 65%. These figures reflect who reports side effects, not underlying risk.

Sex

Female35.7%
Male48.5%
Unknown15.9%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6464.6%
65+35.4%

What is streptozocin used for

Conditions and purposes for which patients were taking streptozocin when the adverse event was reported.

Adrenocortical CarcinomaAcute Myeloid LeukaemiaAdrenal Gland CancerAdrenocortical CarcinomaChemotherapyColon CancerChemotherapyDisease ProgressionGastroenteropancreatic Neuroendocrine Tumour DiseaseGastrointestinal CarcinomaGastrointestinal NeoplasmGastroenteropancreatic Neuroendocrine Tumour DiseaseHepatic LesionHepatic Neuroendocrine TumourIll-defined Disorder

Showing 15 of 42 indications

Streptozocin brand names and reporting trend

Streptozocin is sold under the brand name Zanosar.

Brand names

Zanosar212

Quarterly reports (20042025)

200420202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking streptozocin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.