The most commonly reported side effects of spesolimab include generalised pustular psoriasis, off label use, and pustular psoriasis, based on 287 FDA adverse event reports from 2022 to 2025. 13.2% of reports found the drug to be ineffective.
Percentages show how often each reaction appears relative to total reports for spesolimab.
These are voluntary reports and do not establish that spesolimab caused these reactions.
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Seriousness is determined by the reporter, not by OpenClaim.
Other drugs that appear in adverse event reports alongside spesolimab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
59.6% of spesolimab adverse event reports involve female patients and 27.2% involve male patients. The largest age group is adult at 64%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking spesolimab when the adverse event was reported.
Spesolimab is sold under the brand name Spevigo.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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