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Spectinomycin Side Effects

The most commonly reported side effects of spectinomycin include fatigue, nausea, and cough, based on 91 FDA adverse event reports from 2004 to 2025. 5.5% of reports found the drug to be ineffective.

Spectinomycin side effects

Percentages show how often each reaction appears relative to total reports for spectinomycin.

1
Fatigue12.1%11
2
Nausea7.7%7
3
Cough7.7%7
4
Back Pain6.6%6
5
Abdominal Pain6.6%6
6
Dyspnoea6.6%6
7
Diarrhoea5.5%5
8
Weight Decreased5.5%5
9
Drug Ineffective5.5%5
10
Headache5.5%5
11
Asthenia5.5%5
12
Anxiety5.5%5
13
Pyrexia5.5%5
14
Feeling Abnormal5.5%5
15
Malaise5.5%5

These are voluntary reports and do not establish that spectinomycin caused these reactions.

Report severity

81.3%Serious74 reports
36.3%Hospitalizations33 reports
8.8%Fatal8 reports

Seriousness is determined by the reporter, not by OpenClaim.

Spectinomycin drug interactions

Other drugs that appear in adverse event reports alongside spectinomycin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Teduglutide13.2%12
2
Azithromycin4.4%4
3
Ceftriaxone-sodium4.4%4
4
Sodium-oxybate4.4%4
5
Niacin3.3%3
6
Doxycycline3.3%3
7
Aspirin2.2%2
8
Tenofovir2.2%2
9
Infliximab2.2%2
10
Abatacept2.2%2
11
Etanercept2.2%2
12
Sulfasalazine2.2%2
13
Methotrexate2.2%2
14
Rituximab2.2%2
15
Tocilizumab2.2%2

Taken alongside

1
Ergocalciferol34.1%31
2
Acetaminophen25.3%23
3
Omeprazole23.1%21
4
Cyanocobalamin20.9%19
5
Aspirin18.7%17
6
Calcium17.6%16
7
Loperamide-hydrochloride16.5%15
8
Ascorbic-acid14.3%13
9
Gabapentin14.3%13
10
Levothyroxine-sodium14.3%13
11
Albuterol13.2%12
12
Metoprolol13.2%12
13
Ferrous-sulfate13.2%12
14
Folic-acid12.1%11
15
Fish12.1%11

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports spectinomycin side effects

57.1% of spectinomycin adverse event reports involve female patients and 39.6% involve male patients. The largest age group is adult at 57%. These figures reflect who reports side effects, not underlying risk.

Sex

Female57.1%
Male39.6%
Unknown3.3%

Age group

< 20.0%
2–113.2%
12–173.2%
18–6457.1%
65+36.5%

What is spectinomycin used for

Conditions and purposes for which patients were taking spectinomycin when the adverse event was reported.

Abdominal PainAngiopathyConstipationDiarrhoeaDrug Use For Unknown IndicationDiarrhoeaGastrointestinal DisorderGeneral Physical ConditionGonococcal InfectionGonorrhoeaGonorrhoeaMalabsorptionProduct Used For Unknown IndicationProduct Used For Unknown IndicationShort-bowel Syndrome

Spectinomycin brand names and reporting trend

Spectinomycin is sold under the brand name Trobicin.

Brand names

Trobicin90

Quarterly reports (20042025)

201020152025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking spectinomycin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.