The most commonly reported side effects of sotorasib include non-small cell lung cancer, death, and disease progression, based on 3,058 FDA adverse event reports from 2021 to 2025. 2.2% of reports found the drug to be ineffective.
Percentages show how often each reaction appears relative to total reports for sotorasib.
These are voluntary reports and do not establish that sotorasib caused these reactions.
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Other drugs that appear in adverse event reports alongside sotorasib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
34.0% of sotorasib adverse event reports involve female patients and 35.9% involve male patients. The largest age group is elderly at 63%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking sotorasib when the adverse event was reported.
Showing 15 of 113 indications
Sotorasib is sold under the brand name Lumakras.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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