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Somatrogon Side Effects

The most commonly reported side effects of somatrogon include injection site pain, wrong technique in device usage process, and injection site erythema, based on 1,145 FDA adverse event reports from 2023 to 2025.

#1 Reported: Injection Site PainAll side effects ↓Top Co-Medication: SomatropinDrug interactions ↓67% of Reports Are ChildDemographics ↓

Somatrogon side effects

Percentages show how often each reaction appears relative to total reports for somatrogon.

1
Injection Site Pain66.8%765
2
Wrong Technique In Device Usage Process3.9%45
3
Injection Site Erythema3.9%45
4
Incorrect Dose Administered By Device3.8%44
5
Injection Site Swelling3.4%39
6
Off Label Use2.7%31
7
Headache2.7%31
8
Needle Issue2.6%30
9
Drug Dose Omission By Device2.6%30
10
Patient-device Incompatibility2.6%30
11
Device Mechanical Issue2.5%29
12
Injection Site Mass2.2%25
13
Device Delivery System Issue2.2%25
14
Device Leakage2.1%24
15
Incorrect Dose Administered2.1%24

These are voluntary reports and do not establish that somatrogon caused these reactions.

Report severity

15.6%Serious179 reports
3.7%Hospitalizations42 reports
0.2%Fatal2 reports

Seriousness is determined by the reporter, not by OpenClaim.

Somatrogon drug interactions

Other drugs that appear in adverse event reports alongside somatrogon. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Somatropin1.2%14
2
Hydrocortisone0.3%3
3
Fluticasone<0.1%1
4
Semaglutide<0.1%1
5
Lorlatinib<0.1%1
6
Teduglutide<0.1%1

Taken alongside

1
Levothyroxine-sodium2.1%24
2
Hydrocortisone1.2%14
3
Somatropin0.8%9
4
Cetirizine-hydrochloride0.5%6
5
Montelukast-sodium0.4%5
6
Budesonide0.4%5
7
Buspirone-hydrochloride0.3%4
8
Sertraline-hydrochloride0.3%4
9
Aripiprazole0.3%4
10
Lidocaine0.3%3
11
Amphetamine0.3%3
12
Dextroamphetamine0.3%3
13
Amoxicillin0.3%3
14
Atomoxetine-hydrochloride0.3%3
15
Dexmethylphenidate-hydrochloride0.3%3

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports somatrogon side effects

26.9% of somatrogon adverse event reports involve female patients and 47.2% involve male patients. The largest age group is child at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female26.9%
Male47.2%
Unknown25.9%

Age group

< 20.1%
2–1166.5%
12–1732.5%
18–640.6%
65+0.2%

What is somatrogon used for

Conditions and purposes for which patients were taking somatrogon when the adverse event was reported.

Adrenocortical Insufficiency AcuteBlood Growth HormoneBlood Growth Hormone AbnormalBlood Growth Hormone DecreasedCongenital Growth Hormone DeficiencyDelayed PubertyDwarfismFailure To ThriveGrowth DisorderGrowth Hormone DeficiencyHyperpituitarismHypopituitarismProduct Used For Unknown IndicationPubertySeptic Shock

Showing 15 of 17 indications

Somatrogon brand names and reporting trend

Quarterly reports (2023–2025)

202320242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking somatrogon with another medication?

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