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Sodium Gluconate Side Effects

The most commonly reported side effects of sodium gluconate include pain, renal failure, and injury, based on 1,943 FDA adverse event reports from 2004 to 2025. 2.9% of reports found the drug to be ineffective.

Sodium Gluconate side effects

Percentages show how often each reaction appears relative to total reports for sodium gluconate.

1
Pain12.6%245
2
Renal Failure12.5%243
3
Injury11.8%230
4
Unevaluable Event11.1%215
5
Anxiety10.7%208
6
Death10.1%196
7
Fear9.9%192
8
Emotional Distress8.2%160
9
Renal Injury8.2%160
10
Anhedonia7.8%152
11
Stress7.0%136
12
Renal Impairment6.8%133
13
Multi-organ Failure5.7%110
14
Depression4.1%79
15
Off Label Use3.1%60

These are voluntary reports and do not establish that sodium gluconate caused these reactions.

Report severity

89.0%Serious1,729 reports
39.7%Hospitalizations772 reports
33.5%Fatal650 reports

Seriousness is determined by the reporter, not by OpenClaim.

Sodium Gluconate drug interactions

Other drugs that appear in adverse event reports alongside sodium gluconate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-chloride21.9%426
2
Magnesium-chloride21.5%418
3
Potassium-chloride21.5%417
4
Sodium-acetate21.3%413
5
Icodextrin15.3%298
6
Aprotinin13.9%271
7
Remdesivir4.8%94
8
Dextrose2.6%51
9
Lenalidomide2.6%51
10
Fentanyl2.6%50
11
Propofol2.1%41
12
Methylprednisolone2.0%38
13
Dexamethasone1.6%32
14
Sodium-lactate1.6%31
15
Heparin1.5%29

Taken alongside

1
Potassium-chloride73.8%1,434
2
Sodium-chloride73.6%1,431
3
Magnesium-chloride73.2%1,423
4
Sodium-acetate73.2%1,422
5
Dextrose40.6%788
6
Furosemide18.4%358
7
Heparin16.9%328
8
Insulin13.1%254
9
Acetaminophen13.0%252
10
Fentanyl11.0%214
11
Ergocalciferol10.9%212
12
Aspirin10.9%211
13
Metoprolol10.8%209
14
Midazolam9.6%186
15
Vancomycin9.2%179

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports sodium gluconate side effects

49.9% of sodium gluconate adverse event reports involve female patients and 44.4% involve male patients. The largest age group is adult at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female49.9%
Male44.4%
Unknown5.7%

Age group

< 23.4%
2–111.9%
12–171.2%
18–6451.1%
65+42.5%

What is sodium gluconate used for

Conditions and purposes for which patients were taking sodium gluconate when the adverse event was reported.

Accidental Exposure To ProductAcidosisAcute Myeloid LeukaemiaAcute Respiratory FailureAdenovirus InfectionAnaemiaAnaesthesiaAnaesthetic PremedicationAngioedemaAntiphospholipid SyndromeAplastic AnaemiaAscitesAsthmaAutoimmune Haemolytic AnaemiaAdjuvant Therapy

Showing 15 of 174 indications

Sodium Gluconate brand names and reporting trend

Sodium Gluconate is sold under the brand name Multiple Electrolytes Injection Type 1 Usp Ph 5.5.

Brand names

Multiple Electrolytes Injection Type 1 Usp Ph 5.5128

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking sodium gluconate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.