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Sodium Ascorbate Side Effects

The most commonly reported side effects of sodium ascorbate include vomiting, nausea, and diarrhoea, based on 3,460 FDA adverse event reports from 2004 to 2025. 10.1% of reports found the drug to be ineffective.

Sodium Ascorbate side effects

Percentages show how often each reaction appears relative to total reports for sodium ascorbate.

1
Vomiting16.0%552
2
Nausea14.5%503
3
Drug Ineffective10.1%348
4
Diarrhoea6.7%231
5
Headache6.3%217
6
Abdominal Pain5.5%192
7
Fatigue5.1%176
8
Off Label Use5.1%175
9
Pyrexia5.0%174
10
Pain5.0%173
11
Dehydration4.7%164
12
Malaise4.2%147
13
Hyponatraemia4.1%142
14
Product Taste Abnormal4.0%140
15
Constipation4.0%139

These are voluntary reports and do not establish that sodium ascorbate caused these reactions.

Report severity

76.0%Serious2,630 reports
36.5%Hospitalizations1,263 reports
10.1%Fatal348 reports

Seriousness is determined by the reporter, not by OpenClaim.

Sodium Ascorbate drug interactions

Other drugs that appear in adverse event reports alongside sodium ascorbate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ascorbic-acid64.6%2,235
2
Potassium-chloride63.8%2,206
3
Sodium-chloride63.6%2,200
4
Polyethylene-glycol-335063.5%2,197
5
Sodium-sulfate63.1%2,183
6
Pantoprazole-sodium4.8%166
7
Acetaminophen4.3%148
8
Adalimumab3.8%133
9
Fluticasone3.4%116
10
Hydromorphone-hydrochloride3.2%110
11
Gabapentin3.2%109
12
Etanercept2.9%99
13
Abatacept2.7%94
14
Oxycodone2.7%93
15
Prednisone2.6%91

Taken alongside

1
Ascorbic-acid33.5%1,158
2
Potassium-chloride31.2%1,081
3
Sodium-chloride31.0%1,071
4
Polyethylene-glycol-335030.9%1,070
5
Sodium-sulfate30.6%1,060
6
Acetaminophen12.5%432
7
Omeprazole8.2%284
8
Aspirin7.4%255
9
Pantoprazole-sodium7.0%241
10
Ergocalciferol7.0%241
11
Levothyroxine-sodium6.0%209
12
Prednisone5.3%183
13
Furosemide5.3%183
14
Amlodipine5.3%182
15
Oxycodone4.9%171

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports sodium ascorbate side effects

58.5% of sodium ascorbate adverse event reports involve female patients and 35.6% involve male patients. The largest age group is elderly at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female58.5%
Male35.6%
Unknown5.9%

Age group

< 20.1%
2–110.5%
12–170.6%
18–6448.4%
65+50.4%

What is sodium ascorbate used for

Conditions and purposes for which patients were taking sodium ascorbate when the adverse event was reported.

Abdominal Pain UpperAbdominal PainAdverse Drug ReactionAppendicitisBarium EnemaBowel Movement IrregularityBowel PreparationBlood Iron DecreasedBowel Movement IrregularityBowel PreparationColitis UlcerativeColonic LavageColonoscopyColostomyComputerised Tomogram

Showing 15 of 115 indications

Sodium Ascorbate brand names and reporting trend

Sodium Ascorbate is sold under the brand name Plenvu.

Brand names

Plenvu276

Quarterly reports (20042025)

20042010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking sodium ascorbate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.