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Sodium Acetate Side Effects

The most commonly reported side effects of sodium acetate include toxic anterior segment syndrome, pain, and renal failure, based on 5,695 FDA adverse event reports from 2004 to 2025.

Sodium Acetate side effects

Percentages show how often each reaction appears relative to total reports for sodium acetate.

1
Toxic Anterior Segment Syndrome6.4%365
2
Pain4.5%258
3
Renal Failure4.4%252
4
Injury4.1%231
5
Death3.9%220
6
Off Label Use3.8%218
7
Unevaluable Event3.8%217
8
Endophthalmitis3.8%215
9
Anxiety3.7%212
10
Diarrhoea3.4%195
11
Fear3.4%193
12
Nausea3.4%192
13
Fatigue2.9%166
14
Pyrexia2.9%163
15
Emotional Distress2.8%160

These are voluntary reports and do not establish that sodium acetate caused these reactions.

Report severity

85.9%Serious4,892 reports
36.2%Hospitalizations2,059 reports
19.4%Fatal1,106 reports

Seriousness is determined by the reporter, not by OpenClaim.

Sodium Acetate drug interactions

Other drugs that appear in adverse event reports alongside sodium acetate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Potassium-chloride37.2%2,118
2
Sodium-chloride34.8%1,983
3
Magnesium-chloride32.0%1,822
4
Calcium-chloride30.5%1,738
5
Sodium-citrate21.4%1,217
6
Dextrose9.9%566
7
Amino-acids9.3%530
8
Sodium-gluconate7.3%413
9
Magnesium-sulfate6.3%360
10
Soybean-oil6.0%343
11
Sodium-glycerophosphate5.8%331
12
Icodextrin5.4%305
13
Povidone-iodine5.3%300
14
Aprotinin4.8%271
15
Dexamethasone2.8%162

Taken alongside

1
Potassium-chloride53.4%3,043
2
Sodium-chloride50.2%2,860
3
Magnesium-chloride39.9%2,275
4
Dextrose27.3%1,557
5
Calcium-chloride25.2%1,435
6
Sodium-gluconate25.0%1,422
7
Amino-acids16.1%915
8
Acetaminophen12.7%721
9
Furosemide10.9%618
10
Magnesium-sulfate10.1%577
11
Dexamethasone8.6%491
12
Sodium-citrate8.2%465
13
Soybean-oil8.1%464
14
Heparin8.1%462
15
Sodium-glycerophosphate7.7%440

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports sodium acetate side effects

47.5% of sodium acetate adverse event reports involve female patients and 40.1% involve male patients. The largest age group is adult at 46%. These figures reflect who reports side effects, not underlying risk.

Sex

Female47.5%
Male40.1%
Unknown12.4%

Age group

< 23.1%
2–112.8%
12–171.6%
18–6446.3%
65+46.2%

What is sodium acetate used for

Conditions and purposes for which patients were taking sodium acetate when the adverse event was reported.

Accidental Exposure To ProductAcidosisAcidosis HyperchloraemicAcute Kidney InjuryAcute Myeloid LeukaemiaAcute Respiratory FailureAddison^s DiseaseAdenovirus InfectionAdjuvant TherapyAdverse EventAnaemiaAnaesthesiaAnaesthetic PremedicationAnalgesic TherapyAngioedema

Showing 15 of 423 indications

Sodium Acetate brand names and reporting trend

Sodium Acetate is sold under the brand name Veinamine 8%.

Brand names

Veinamine 8%376

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking sodium acetate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.