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Sevabertinib Side Effects

The most commonly reported side effects of sevabertinib include fungal skin infection, acute kidney injury, and diarrhoea, based on 2 FDA adverse event reports from 2016 to 2025.

Sevabertinib side effects

Percentages show how often each reaction appears relative to total reports for sevabertinib.

1
Fungal Skin Infection50.0%1
2
Acute Kidney Injury50.0%1
3
Diarrhoea50.0%1

These are voluntary reports and do not establish that sevabertinib caused these reactions.

Report severity

50.0%Serious1 reports
50.0%Hospitalizations1 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Sevabertinib drug interactions

Other drugs that appear in adverse event reports alongside sevabertinib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ecallantide50.0%1
2
Irbesartan50.0%1

Taken alongside

1
Fenofibrate50.0%1
2
Diphenhydramine50.0%1
3
Icatibant-acetate50.0%1
4
Sterile50.0%1
5
Sodium-chloride50.0%1
6
Doxycycline50.0%1
7
Ranitidine50.0%1
8
Prednisone50.0%1
9
Levothyroxine-sodium50.0%1
10
Epinephrine50.0%1
11
Escitalopram-oxalate50.0%1
12
Azithromycin50.0%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports sevabertinib side effects

50.0% of sevabertinib adverse event reports involve female patients and 50.0% involve male patients. The largest age group is elderly at 100%. These figures reflect who reports side effects, not underlying risk.

Sex

Female50.0%
Male50.0%
Unknown0.0%

Age group

< 20.0%
2–110.0%
12–170.0%
18–640.0%
65+100.0%

What is sevabertinib used for

Conditions and purposes for which patients were taking sevabertinib when the adverse event was reported.

Egfr Gene MutationHer2 Mutant Non-small Cell Lung CancerHereditary Angioedema

Sevabertinib brand names and reporting trend

Sevabertinib is sold under the brand name Hyrnuo.

Brand names

Hyrnuo4

Quarterly reports (20162025)

20162025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking sevabertinib with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.