The most commonly reported side effects of sepiapterin include fatigue, nephrolithiasis, and endometrial cancer stage i, based on 13 FDA adverse event reports from 2013 to 2025.
Percentages show how often each reaction appears relative to total reports for sepiapterin.
These are voluntary reports and do not establish that sepiapterin caused these reactions.
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Other drugs that appear in adverse event reports alongside sepiapterin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
76.9% of sepiapterin adverse event reports involve female patients and 23.1% involve male patients. The largest age group is elderly at 60%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking sepiapterin when the adverse event was reported.
Sepiapterin is sold under the brand name Sephience.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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